http://www.cnr.it/ontology/cnr/individuo/prodotto/ID5101
The controversial nuclear matrix: a balanced point of view (Articolo in rivista)
- Type
- Label
- The controversial nuclear matrix: a balanced point of view (Articolo in rivista) (literal)
- Anno
- 2002-01-01T00:00:00+01:00 (literal)
- Alternative label
Martelli A.M., Falcieri E., Zweyer M., Bortul R., G Tabellini., Cappellini A., Cocco L., Manzoli L. (2002)
The controversial nuclear matrix: a balanced point of view
in Histology and histopathology
(literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- Martelli A.M., Falcieri E., Zweyer M., Bortul R., G Tabellini., Cappellini A., Cocco L., Manzoli L. (literal)
- Pagina inizio
- Pagina fine
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
- Rivista
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#note
- Note
- ISI Web of Science (WOS) (literal)
- Titolo
- The controversial nuclear matrix: a balanced point of view (literal)
- Abstract
- The nuclear matrix is defined as the residual framework after the removal
of the nuclear envelope, chromatin, and soluble components by sequential
extractions. According to several investigators the nuclear matrix
provides the structural basis for intranuclear order. However, the
existence itself and the nature of this structure is still uncertain.
Although the techniques used for the visualization of the nuclear matrix
have improved over the years, it is still unclear to what extent the
isolated nuclear matrix corresponds to an in vivo existing structure.
Therefore, considerable skepticism continues to surround the nuclear
matrix fraction as an accurate representation of the situation in living
cells. Here, we summarize the experimental evidence in favor of, or
against, the presence of a diffuse nucleoskeleton as a facilitating
organizational nonchromatin structure of the nucleus. (literal)
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