Oligothiophene-5-Labeled Deoxyuridines for the Detection of Single Nucleotide Polymorphisms (Articolo in rivista)

Type
Label
  • Oligothiophene-5-Labeled Deoxyuridines for the Detection of Single Nucleotide Polymorphisms (Articolo in rivista) (literal)
Anno
  • 2008-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1021/bc7002555 (literal)
Alternative label
  • M. L. Capobianco, A. Cazzato, S. Alesi, G. Barbarella. (2008)
    Oligothiophene-5-Labeled Deoxyuridines for the Detection of Single Nucleotide Polymorphisms
    in Bioconjugate chemistry
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • M. L. Capobianco, A. Cazzato, S. Alesi, G. Barbarella. (literal)
Pagina inizio
  • 171 (literal)
Pagina fine
  • 177 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 19 (literal)
Rivista
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#note
  • in press (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo
  • 1 (literal)
Note
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • 1. ISOF CNR, I-40129 Bologna, Italy (literal)
Titolo
  • Oligothiophene-5-Labeled Deoxyuridines for the Detection of Single Nucleotide Polymorphisms (literal)
Abstract
  • We report the synthesis of four oligothiophene-5-labeled deoxyuridines. These modified fluorescent nucleosides have been incorporated into oligodeoxynucleotides designed to be used as probes to discriminate, through changes in fluorescence emission, between hybridization with a perfectly complementary strand and that with a single nucleotide mismatch facing the modified uridines. Upon hybridization, remarkable differences (up to 47%) of the emitted light, depending on the uridine facing base, were observed. (literal)
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