Extremely-low frequency magnetic field modulates differentiation and maturation of human and rat primary and multipotent stem cells (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• Extremely-low frequency magnetic field modulates differentiation and maturation of human and rat primary and multipotent stem cells (Articolo in rivista) (literal)

Anno

• 2010-01-01T00:00:00+01:00 (literal)

Alternative label

• Ledda M.*, De Carlo F.*, D’Emilia E.**, Giuliani L.**, Grimaldi S.*, Lisi A.* (2010)
  Extremely-low frequency magnetic field modulates differentiation and maturation of human and rat primary and multipotent stem cells
  in European journal of oncology
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Ledda M.*, De Carlo F.*, D’Emilia E.**, Giuliani L.**, Grimaldi S.*, Lisi A.* (literal)

Pagina inizio

• 135 (literal)

Pagina fine

• 147 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#altreInformazioni

• Eur. J. Oncol. Library, vol. 5 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 5 (literal)

Rivista

• European journal of oncology (Rivista)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• * Institute of Neurobiology and Molecular Medicine CNR, Rome, Italy:Institute of Translational Pharmacology IFT ** National Institute for Prevention and Safety at Work (ISPEL), Rome, Italy (literal)

Titolo

• Extremely-low frequency magnetic field modulates differentiation and maturation of human and rat primary and multipotent stem cells (literal)

Abstract

• In the last 15 years, we reported numerous biological effects of extremely-lowfrequency electromagnetic fields (ELF-EMF) on different cells types. We showed morphological and cytoskeletal changes in keratinocyte cell lines exposed to a 50-Hz 2 mT ELF-EMF. Furthermore, we reported that very high magnetic field (MF) intensity promotes maturation and differentiation in newborn cerebellar granule cells, and a 50-Hz 2 mT ELF-EMF produced a sudden increase in the intracellular calcium level in rat anterior pituitary-derived AtT20 D16V cells followed by a reorganization of the cytoskeletal network via polymerization of actin and differentiation of protein expression. Recently, we showed that a combination of static and alternate EMFs, tuned to Ca2+ ion cyclotron energy resonance (Ca2+-ICR) was able to trigger human cardiac stem sell-specific differentiation. In the present review, we report a summary of the most relevant results that we have reached in the last 7 years, in particular, we focus the attention on the differentiation effect of ELF-EMF on 3 different types of primary cell culture: human oral keratinocytes (HOK), newborn rat cerebellar granule neurons (CGN), and human adult cardiac stem cells (CSC). (literal)

Prodotto di

• Protocolli di combinazioni di campi elettrici, magnetici ed elettromagnetici pulsati per il trasferimento di molecole ad attività farmacologica in vitro ed in vivo (ME.P06.012.002) (Modulo)
• Studio dell'interazione tra campi elettromagnetici e cellule eucariotiche (ME.P06.012.001) (Modulo)
• Istituto di neurobiologia e medicina molecolare (INMM) (Istituto)

Autore CNR

• ANTONELLA LISI (Unità di personale interno)
• SETTIMIO GRIMALDI (Persona)
• MARIO LEDDA (Persona)

Insieme di parole chiave

• Parole chiave di "Extremely-low frequency magnetic field modulates differentiation and maturation of human and rat primary and multipotent stem cells" (Insieme di parole chiave)

Incoming links:

Autore CNR di

• ANTONELLA LISI (Unità di personale interno)
• MARIO LEDDA (Persona)
• SETTIMIO GRIMALDI (Persona)

Prodotto

• Istituto di neurobiologia e medicina molecolare (INMM) (Istituto)
• Studio dell'interazione tra campi elettromagnetici e cellule eucariotiche (ME.P06.012.001) (Modulo)
• Protocolli di combinazioni di campi elettrici, magnetici ed elettromagnetici pulsati per il trasferimento di molecole ad attività farmacologica in vitro ed in vivo (ME.P06.012.002) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• European journal of oncology (Rivista)

Insieme di parole chiave di

• Parole chiave di "Extremely-low frequency magnetic field modulates differentiation and maturation of human and rat primary and multipotent stem cells" (Insieme di parole chiave)