Conjunctivally administered NGF antibody reduces pain sensitivity and anxiety-like behavioral responses in aged female mice (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Conjunctivally administered NGF antibody reduces pain sensitivity and anxiety-like behavioral responses in aged female mice (Articolo in rivista) (literal)

Anno

• 2010-01-01T00:00:00+01:00 (literal)

Alternative label

• Berry A.1), Aloe L.2), Rossi S.2), Bonsignore L.T.1), Capone F.1), Alleva E.1), Cirulli F.1) (2010)
  Conjunctivally administered NGF antibody reduces pain sensitivity and anxiety-like behavioral responses in aged female mice
  in Behavioural brain research
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Berry A.1), Aloe L.2), Rossi S.2), Bonsignore L.T.1), Capone F.1), Alleva E.1), Cirulli F.1) (literal)

Pagina inizio

• 284 (literal)

Pagina fine

• 287 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 210/2 (literal)

Rivista

• Behavioural brain research (Rivista)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• 1) - Behavioural Neuroscience Section, Department of Cell Biology and Neurosciences, Istituto Superiore di Sanità, Viale Regina Elena 299, Rome, Italy; 2) - Institute of Neurobiology and Molecular Medicine, CNR, NGF Section, Via del Fosso di Fiorano, 64/65, I-00143 Rome, Italy (literal)

Titolo

• Conjunctivally administered NGF antibody reduces pain sensitivity and anxiety-like behavioral responses in aged female mice (literal)

Abstract

• This study reports that peripheral administration of Nerve Growth Factor antibodies (ANA) affects behavior in aged female CD-1 mice. ANA increased the propensity of mice to stay and perform behaviors in the anxiogenic open arms of the maze, lowered pain sensitivity and reduced behavioral flexibility in a Morris water maze task, also reducing ChAT immunoreactivity in the basal forebrain. These findings support the hypothesis that topical eye application can represent an alternative route for delivering biologically active compounds into the brain allowing studying the role of NGF on brain cell function. (literal)

Prodotto di

• Funzioni del S.N./Neurotrofine (SV.P16.007.001) (Modulo)
• Istituto di neurobiologia e medicina molecolare (INMM) (Istituto)

Autore CNR

• LUIGI ALOE (Unità di personale interno)
• Simona Rossi (Unità di personale esterno)

Insieme di parole chiave

• Parole chiave di "Conjunctivally administered NGF antibody reduces pain sensitivity and anxiety-like behavioral responses in aged female mice" (Insieme di parole chiave)

Incoming links:

Prodotto

• Istituto di neurobiologia e medicina molecolare (INMM) (Istituto)
• Funzioni del S.N./Neurotrofine (SV.P16.007.001) (Modulo)

Autore CNR di

• LUIGI ALOE (Unità di personale interno)
• Simona Rossi (Unità di personale esterno)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Behavioural brain research (Rivista)

Insieme di parole chiave di

• Parole chiave di "Conjunctivally administered NGF antibody reduces pain sensitivity and anxiety-like behavioral responses in aged female mice" (Insieme di parole chiave)