Variables influencing quality of life and disability in Charcot Marie Tooth (CMT) patients: Italian multicentre study. (Articolo in rivista)

Type
Label
  • Variables influencing quality of life and disability in Charcot Marie Tooth (CMT) patients: Italian multicentre study. (Articolo in rivista) (literal)
Anno
  • 2006-01-01T00:00:00+01:00 (literal)
Alternative label
  • Padua L, Aprile I, Cavallaro T, Commodari I, La Torre G, Pareyson D, Quattrone A, Rizzuto N, Vita G, Tonali P, Schenone A; Italian CMT QoL Study Group. (2006)
    Variables influencing quality of life and disability in Charcot Marie Tooth (CMT) patients: Italian multicentre study.
    in Neurological sciences (Testo stamp.)
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Padua L, Aprile I, Cavallaro T, Commodari I, La Torre G, Pareyson D, Quattrone A, Rizzuto N, Vita G, Tonali P, Schenone A; Italian CMT QoL Study Group. (literal)
Pagina inizio
  • 417 (literal)
Pagina fine
  • 423 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 27 (literal)
Rivista
Note
  • ISI Web of Science (WOS) (literal)
Titolo
  • Variables influencing quality of life and disability in Charcot Marie Tooth (CMT) patients: Italian multicentre study. (literal)
Abstract
  • The purpose of this study was to assess the variables that influence quality of life (QoL) and disability in patients with Charcot-Marie-Tooth disease (CMT). We performed a prospective multicentre study using validated clinical disability and QoL measurements. Multivariate analysis was performed using QoL as a dependent variable and duration of symptoms, age, gender and CMT type, depression and disability measurements as independent variables. We enrolled 211 patients. QoL was highly significantly deteriorated with respect to the Italian normative sample. The physical aspect of QoL was mainly related to disability but it does not increase with the age, probably because of an adaptation between expectation and reality. The mental QoL is influenced by depression (hence we have to consider this aspect approaching CMT patients). Moreover, we observed that women complained of more severe symptoms than men. Finally, some CMT subtypes are related to more severe bodily pain symptoms than others. Multiperspective assessment of CMT showed new aspects of this disease, mainly regarding (1) differences between men and women and (2) the crucial role of pain and depression. (literal)
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