http://www.cnr.it/ontology/cnr/individuo/prodotto/ID48644

Magnetic Nanoparticles in biomedicine Recent advances (Articolo in rivista)

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Magnetic Nanoparticles in biomedicine Recent advances (Articolo in rivista) (literal)

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Lascialfari, Alessandro; Sangregorio, Claudio (2011)
Magnetic Nanoparticles in biomedicine Recent advances
in Chimica oggi (Online)
(literal)

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[Lascialfari, Alessandro] Univ Milan, I-20134 Milan, Italy; INSTM, Dept Mol Sci Appl Biosyst, I-20134 Milan, Italy; CNR NANO S3, I-41100 Modena, Italy. [Sangregorio, Claudio] CNR ISTM, I-20133 Milan, Italy; INSTM, I-20133 Milan, Italy. (literal)

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Abstract

In recent years, several papers in the literature considered the Importance of iron and other transition metal based compounds not only in the preparation of magnetic nanostructured contrast media for MRI. SQUID and biosensing detection, but also in the manufacturing of labelled compounds able to track cells and/or tissues in vivo and ex vivo. In this way objects for targeting specific tissues can be obtained, pushing the diagnosis capability to the molecular level. In the last fifteen years, this diagnostics ability has been joint to the possibility of using the magnetic nanoparticles for delivering drugs and for releasing heat locally, thus allowing to obtain theranostic agents for the realization of the find-fight and follow approach in the treatment of tumour and of other diseases. (literal)

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