Glaucoma alters the expression of NGF and NGF receptors in visual cortex and geniculate nucleus of rats: Effect of eye NGF application (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• Glaucoma alters the expression of NGF and NGF receptors in visual cortex and geniculate nucleus of rats: Effect of eye NGF application (Articolo in rivista) (literal)

Anno

• 2009-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1016/j.visres.2008.09.024 (literal)

Alternative label

• Sposato V. 1; Parisi V. 2; Manni L.1; Antonucci M.T.1; Di Fausto V.1; Sornelli F.1; Aloe L.1 (2009)
  Glaucoma alters the expression of NGF and NGF receptors in visual cortex and geniculate nucleus of rats: Effect of eye NGF application
  in Vision research (Oxf.)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Sposato V. 1; Parisi V. 2; Manni L.1; Antonucci M.T.1; Di Fausto V.1; Sornelli F.1; Aloe L.1 (literal)

Pagina inizio

• 54 (literal)

Pagina fine

• 63 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#altreInformazioni

• Online 11 November 2008 - [doi:10.1016/j.visres.2008.09.024] (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 49 (literal)

Rivista

• Vision research (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 1 (literal)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• 1 = Institute of Neurobiology and Molecular Medicine, Section of Neurobiology, CNR, Rome, Italy; 2 = IRCCS Bietti Foundation, Rome, Italy (literal)

Titolo

• Glaucoma alters the expression of NGF and NGF receptors in visual cortex and geniculate nucleus of rats: Effect of eye NGF application (literal)

Abstract

• We investigated the effect of glaucoma (GL) on nerve growth factor (NGF) presence in two brain visual areas. Rats with elevated intraocular pressure (EIOP), induced by hypertonic saline injection in the episcleral vein, were treated with eye topical application of saline or NGF. Rats were subsequently sacrificed, and brain tissues were used for immunohistochemical, biochemical, and molecular analyses. We found that GL alters the basal level of NGF and NGF receptors in brain visual centers and that NGF eye application normalized these deficits. These findings demonstrate that the reduced presence of NGF can arise due to degenerative events in retinal and brain visual areas. (literal)

Prodotto di

• Funzioni del S.N./Neurotrofine (SV.P16.007.001) (Modulo)
• Istituto di neurobiologia e medicina molecolare (INMM) (Istituto)

Autore CNR

• valentina sposato (Persona)
• LUIGI ALOE (Unità di personale esterno)
• LUIGI MANNI (Persona)

Incoming links:

Prodotto

• Istituto di neurobiologia e medicina molecolare (INMM) (Istituto)
• Funzioni del S.N./Neurotrofine (SV.P16.007.001) (Modulo)

Autore CNR di

• LUIGI MANNI (Persona)
• valentina sposato (Persona)
• LUIGI ALOE (Unità di personale esterno)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Vision research (Rivista)