Collisionally induced fragmentation of [M-H](-) species of resveratrol and piceatannol investigated by deuterium labelling and accurate mass measurements (Articolo in rivista)

Type
Label
  • Collisionally induced fragmentation of [M-H](-) species of resveratrol and piceatannol investigated by deuterium labelling and accurate mass measurements (Articolo in rivista) (literal)
Anno
  • 2008-01-01T00:00:00+01:00 (literal)
Alternative label
  • Stella, L.; De Rosso, M.; Panighel, A.; Vedova, A. D.; Flamini, R.; Traldi, P. (2008)
    Collisionally induced fragmentation of [M-H](-) species of resveratrol and piceatannol investigated by deuterium labelling and accurate mass measurements
    in RCM. Rapid communications in mass spectrometry
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Stella, L.; De Rosso, M.; Panighel, A.; Vedova, A. D.; Flamini, R.; Traldi, P. (literal)
Pagina inizio
  • 3867 (literal)
Pagina fine
  • 3872 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 22 (literal)
Rivista
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#note
  • DOI: 10.1002/rcm.3811 (literal)
Note
  • ISI Web of Science (WOS) (literal)
Titolo
  • Collisionally induced fragmentation of [M-H](-) species of resveratrol and piceatannol investigated by deuterium labelling and accurate mass measurements (literal)
Abstract
  • Resveratrol (3,5,4'-trihydroxystilbene) and piceatannol (3,4,3',5'-tetrahydroxy-trans-stilbene) are phytoalexins present in red grapes and wines. In vitro studies have revealed that piceatannol blocks LMP2A, a viral protein-tyrosine kinase implicated in leukemia, non-Hodgkin's lymphoma and other diseases associated with the Epstein-Barr virus, and has an antimelanoma effect on human melanoma cells. Resveratrol has several beneficial effects on human health, such as anticancer, cardioprotection, antioxidant, inhibition of platelet aggregation and anti-inflammatory activity. In this investigation, the collisional behaviour of deprotonated resveratrol and piceatannol obtained under electrospray conditions is described. The mechanisms involved in the fragmentation pattern of [M-H](-) species of the two compounds were investigated by performing MSn experiments, deuterium labelling and accurate mass measurements. Copyright (C) 2008 John Wiley & Sons, Ltd. (literal)
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