http://www.cnr.it/ontology/cnr/individuo/prodotto/ID48340
Collisionally induced fragmentation of [M-H](-) species of resveratrol and piceatannol investigated by deuterium labelling and accurate mass measurements (Articolo in rivista)
- Type
- Label
- Collisionally induced fragmentation of [M-H](-) species of resveratrol and piceatannol investigated by deuterium labelling and accurate mass measurements (Articolo in rivista) (literal)
- Anno
- 2008-01-01T00:00:00+01:00 (literal)
- Alternative label
Stella, L.; De Rosso, M.; Panighel, A.; Vedova, A. D.; Flamini, R.; Traldi, P. (2008)
Collisionally induced fragmentation of [M-H](-) species of resveratrol and piceatannol investigated by deuterium labelling and accurate mass measurements
in RCM. Rapid communications in mass spectrometry
(literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- Stella, L.; De Rosso, M.; Panighel, A.; Vedova, A. D.; Flamini, R.; Traldi, P. (literal)
- Pagina inizio
- Pagina fine
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
- Rivista
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#note
- DOI: 10.1002/rcm.3811 (literal)
- Note
- ISI Web of Science (WOS) (literal)
- Titolo
- Collisionally induced fragmentation of [M-H](-) species of resveratrol and piceatannol investigated by deuterium labelling and accurate mass measurements (literal)
- Abstract
- Resveratrol (3,5,4'-trihydroxystilbene) and piceatannol (3,4,3',5'-tetrahydroxy-trans-stilbene) are phytoalexins present in red grapes and wines. In vitro studies have revealed that piceatannol blocks LMP2A, a viral protein-tyrosine kinase implicated in leukemia, non-Hodgkin's lymphoma and other diseases associated with the Epstein-Barr virus, and has an antimelanoma effect on human melanoma cells. Resveratrol has several beneficial effects on human health, such as anticancer, cardioprotection, antioxidant, inhibition of platelet aggregation and anti-inflammatory activity. In this investigation, the collisional behaviour of deprotonated resveratrol and piceatannol obtained under electrospray conditions is described. The mechanisms involved in the fragmentation pattern of [M-H](-) species of the two compounds were investigated by performing MSn experiments, deuterium labelling and accurate mass measurements. Copyright (C) 2008 John Wiley & Sons, Ltd. (literal)
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- Autore CNR
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