http://www.cnr.it/ontology/cnr/individuo/prodotto/ID47000
Volumetrics of the caudate nucleus: reliability and validity of a new manual tracing protocol (Articolo in rivista)
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- Label
- Volumetrics of the caudate nucleus: reliability and validity of a new manual tracing protocol (Articolo in rivista) (literal)
- Anno
- 2008-01-01T00:00:00+01:00 (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
- 10.1016/j.pscychresns.2007.07.005 (literal)
- Alternative label
Looi JCL; Lindberg O; Liberg B; Tatham V; Kumar; Maller J; Millard E; Sachdev P; Hogberg G; Pagani M; Botes L; Engman E-L; Zhang Y Svensson L; Wahlund, L-O (2008)
Volumetrics of the caudate nucleus: reliability and validity of a new manual tracing protocol
in Psychiatry research. Neuroimaging (Print); Elsevier Ireland Ltd., Clare (Irlanda)
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- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- Looi JCL; Lindberg O; Liberg B; Tatham V; Kumar; Maller J; Millard E; Sachdev P; Hogberg G; Pagani M; Botes L; Engman E-L; Zhang Y Svensson L; Wahlund, L-O (literal)
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- ISI Web of Science (WOS) (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
- Research Centre for the Neurosciences of Ageing, Academic Unit of Psychological Medicine, Australian National University Medical School, The Canberra Hospital, Australian Capital Territory, Australia
Laboratory of Neuro Imaging, Department of Neurology, David Geffen School of Medicine, UCLA, Los Angeles, California, USA
Karolinska Institute, Department of Neurobiology, Caring Sciences & Society, Division of Clinical Geriatrics, Stockholm, Sweden
Consultation-Liaison Psychiatry, Department of Psychological Medicine, National University of Singapore, Singapore
Alfred Psychiatry Research Centre, Monash University & Centre for Mental Health Research, Australian National University, Canberrra, Australia
School of Psychiatry, Faculty of Medicine, University of New South Wales, Prince of Wales Hospital, Sydney, Australia
Neuropsychiatric Institute, Prince of Wales Hospital, Sydney, Australia
Department of Clinical Neuroscience, Section for Psychiatry, Huddinge, Karolinska Institute, Stockholm, Sweden
Institute of Cognitive Sciences and Technologies, CNR, Rome, Italy and Department of Nuclear Medicine, Karolinska Hospital, Stockholm, Sweden
Karolinska University Hospital, Hospital Physics & Radiology, Stockholm, Sweden (literal)
- Titolo
- Volumetrics of the caudate nucleus: reliability and validity of a new manual tracing protocol (literal)
- Abstract
- Our aim was to develop a reliable and valid manual segmentation protocol for tracing the caudate nucleus in MRI for volumetric and, potentially, shape analysis of the caudate. Using the protocol, two inter- and intra-rater reliability studies were conducted using five different raters on two different image analysis platforms (ANALYZE, Mayo Biomedical Imaging Resource, Rochester MI, USA & HERMES, Nuclear Diagnostics AB, Stockholm, Sweden). Reference images for the detailed protocol are described. Two studies were performed. In study one: the intra-rater class correlation ICC(1,1) for an experienced rater (JCLL) using this protocol for the caudate nucleus volumes was evaluated by repeating right and left caudate measurements on 10 scans, (20 comparisons) and was 0.972. The inter-rater class correlation ICC (1,k) with OL was 0.922 on 5 scans (10 comparisons) and with BL was 0.960 5 scans (10 comparisons). In study two: VT obtained an intra-rater class correlation of 0.9 on 5 scans (involving 10 comparisions e.g. right and left caudate). Inter-rater class correlation ICC (1,k) was 0.988 on 5 scans (again involving 10 comparisons) with EM. We therefore developed a novel, reliable- and reference image-based, method of outlining the caudate nucleus with reference to axial MRI scans, usable in two different image analysis laboratories, across two different sets number of tracers reliably, and across software platforms. This method is therefore potentially usable for any image analysis package capable of displaying and measuring outlined voxels from MRI brain scans. (literal)
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