Effects of C-fullerenes and single carbon nanotubes on murine and human macrophage cells. (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Effects of C-fullerenes and single carbon nanotubes on murine and human macrophage cells. (Articolo in rivista) (literal)

Anno

• 2006-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1016/j.carbon.2005.11.009 (literal)

Alternative label

• Fiorito S.a,c; Serafino A.L.b; Andreola F.b; Bernier P.c (2006)
  Effects of C-fullerenes and single carbon nanotubes on murine and human macrophage cells.
  in Carbon
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Fiorito S.a,c; Serafino A.L.b; Andreola F.b; Bernier P.c (literal)

Pagina inizio

• 1100 (literal)

Pagina fine

• 1105 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#altreInformazioni

• Impact Factor (2006) = 3.884 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 44 (literal)

Rivista

• Carbon (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 6 (literal)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• a = Department of Experimental Medicine, University of Rome La Sapienza-CNR, 00133 Rome, Italy; b = Institute of Neurobiology and Molecular Medicine, Rome, Italy; c = Groupe de Dynamique des Phases Condensee, CNRS, 34095 Montpellier Cedex 05, France (literal)

Titolo

• Effects of C-fullerenes and single carbon nanotubes on murine and human macrophage cells. (literal)

Abstract

• The discovery in 1985 of C-fullerenes, a novel carbon allotrope with a polygonal structure made up solely by 60 carbon atoms, and in 1991 of C-nanotubes, thin carbon filaments (1-3 ?m in length and 0.001 ?m in diameter) with extraordinary mechanical properties, opened a wide field of activity in carbon research. While toxicity and biocompatibility of C-fullerenes have been widely investigated, literature data concerning the biological properties and biotoxicity of C-nanotubes are poor and contradictory. Here we test the ability of highly purified C-Single-Walled-Nanotubes (SWNTs) and C-fullerenes to elicit an inflammatory response by murine and human macrophage cells in vitro. In order to determine the potential of these C-derivatives as biological inducers of inflammatory reactions we evaluate the ability of C-single-walled nanotubes and C-fullerenes to induce the release of NO by murine macrophages cells, to stimulate the phagocytic activity of human macrophage cells and to be cytotoxic against these cells. We show that SWNTs-C-nanotubes, when highly purified, as well as C-fullerenes, do not stimulate the release of NO by murine macrophage cells in culture, their uptake by human macrophage cells is very low, and they possess a very low toxicity against human macrophage cells. (literal)

Prodotto di

• Istituto di neurobiologia e medicina molecolare (INMM) (Istituto)
• Target Molecolari, Modelli preclinici e Immunoterapia (ME.P03.006.001) (Modulo)

Autore CNR

• SILVANA FIORITO (Persona)
• FEDERICA ANDREOLA (Persona)
• ANNALUCIA SERAFINO (Persona)

Incoming links:

Autore CNR di

• ANNALUCIA SERAFINO (Persona)
• FEDERICA ANDREOLA (Persona)
• SILVANA FIORITO (Persona)

Prodotto

• Istituto di neurobiologia e medicina molecolare (INMM) (Istituto)
• Target Molecolari, Modelli preclinici e Immunoterapia (ME.P03.006.001) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Carbon (Rivista)