Effect of resveratrol on proliferation and telomerase activity of human colon cancer cells in vitro. (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Effect of resveratrol on proliferation and telomerase activity of human colon cancer cells in vitro. (Articolo in rivista) (literal)

Anno

• 2006-01-01T00:00:00+01:00 (literal)

Alternative label

• Fuggetta M.P.1; Lanzilli G.1; Tricarico M.1; Cottarelli A.1; Falchetti R.1; Ravagnan G.3; Bonmassar E.1,2 (2006)
  Effect of resveratrol on proliferation and telomerase activity of human colon cancer cells in vitro.
  in Journal of experimental & clinical cancer research (Testo stamp.)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Fuggetta M.P.1; Lanzilli G.1; Tricarico M.1; Cottarelli A.1; Falchetti R.1; Ravagnan G.3; Bonmassar E.1,2 (literal)

Pagina inizio

• 189 (literal)

Pagina fine

• 193 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#altreInformazioni

• *Authors contributed equally to this work. Impact Factor = 0.869 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 25 (literal)

Rivista

• Journal of experimental & clinical cancer research (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 2 (literal)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• 1 = Institute of Neurobiology and Molecular Medicine, National Research Council, CNR, Area Ricerca Tor Vergata, Rome, Italy; 2 = Department of Neuroscience, University of Tor Vergata, Rome; 3 = Department of Environmental Science, Ca' Foscari, University of Venice, Venice, Italy (literal)

Titolo

• Effect of resveratrol on proliferation and telomerase activity of human colon cancer cells in vitro. (literal)

Abstract

• A number of studies performed in our laboratory and elsewhere, showed that resveratrol is able to prevent carcinogenesis and to impair tumor growth and progression. In order to provide additional information on the pleiotropic effects of resveratrol on malignant cells, the present study was performed to test the in vitro influence of the compound on the growth and TLMA of HT-29 and WiDr human colon cancer cell lines. The results confirmed that resveratrol has a direct, dose dependent, inhibitory effect on cell proliferation in both lines. In addition, for the first time, relatively high concentrations of this compound were found to be able to substantially down-regulate telomerase activity. These preliminary results further support the potential role of resveratrol in chemoprevention/chemotherapy of human colon tumor cells and provide the rational basis for novel strategies in cancer control. (literal)

Prodotto di

• Immunofarmacologia di sostanze naturali e di sintesi nell’ambito della crescita neoplastica in vivo ed in vitro. (ME.P03.006.002) (Modulo)
• Istituto di neurobiologia e medicina molecolare (INMM) (Istituto)

Autore CNR

• GIULIA LANZILLI (Persona)
• ANDREA COTTARELLI (Persona)
• MARIA TRICARICO (Persona)
• MARIA PIA FUGGETTA (Unità di personale interno)

Insieme di parole chiave

• Keywords of "Effect of resveratrol on proliferation and telomerase activity of human colon cancer cells in vitro." (Insieme di parole chiave)

Incoming links:

Autore CNR di

• GIULIA LANZILLI (Persona)
• MARIA TRICARICO (Persona)
• MARIA PIA FUGGETTA (Unità di personale interno)
• ANDREA COTTARELLI (Persona)

Prodotto

• Istituto di neurobiologia e medicina molecolare (INMM) (Istituto)
• Immunofarmacologia di sostanze naturali e di sintesi nell’ambito della crescita neoplastica in vivo ed in vitro. (ME.P03.006.002) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Journal of experimental & clinical cancer research (Rivista)

Insieme di parole chiave di

• Keywords of "Effect of resveratrol on proliferation and telomerase activity of human colon cancer cells in vitro." (Insieme di parole chiave)