Highlighting chromosome loops in DNA-picked chromatin (DPC). (Articolo in rivista)

Type
Label
  • Highlighting chromosome loops in DNA-picked chromatin (DPC). (Articolo in rivista) (literal)
Anno
  • 2011-01-01T00:00:00+01:00 (literal)
Alternative label
  • Abbondanza C, De Rosa C, Ombra MN, Aceto F, Medici N, Altucci L, Moncharmont B, Puca GA, Porcellini A, Avvedimento EV, Perillo B. (2011)
    Highlighting chromosome loops in DNA-picked chromatin (DPC).
    in Epigenetics
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Abbondanza C, De Rosa C, Ombra MN, Aceto F, Medici N, Altucci L, Moncharmont B, Puca GA, Porcellini A, Avvedimento EV, Perillo B. (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 6 (literal)
Rivista
Note
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • Dipartimento di Patologia Generale, Seconda Universit√† degli Studi di Napoli; Naples, Italy. Istituto di Scienze dell'Alimentazione, CNR, Avellino, Italt (literal)
Titolo
  • Highlighting chromosome loops in DNA-picked chromatin (DPC). (literal)
Abstract
  • Growing evidence supports the concept that dynamic intra- and inter-chromosomal links between specific loci contribute to the creation of cell-type specific gene expression profiles. Therefore, analysis of the establishment of peculiar functional correlations between sites, also distant on linear DNA, that govern the transcriptional process appears to be of fundamental relevance. We propose here an experimental approach showing that 17¬≤-estradiol-induced transcription associates to formation of loops between the promoter and termination regions of hormone-responsive genes. This strategy reveals as a tool to be also suitably used, in conjunction with automated techniques, for an extensive analysis of sites shared by multiple genes for induced expression. (literal)
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