NERVE GROWTH FACTOR: NEUROTROPHIN OR CYTOKINE? (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• NERVE GROWTH FACTOR: NEUROTROPHIN OR CYTOKINE? (Articolo in rivista) (literal)

Anno

• 2003-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1159/000070922 (literal)

Alternative label

• Bonini S., Rasi G., Bracci-Laudiero M.L., Procoli A., Aloe L. (2003)
  NERVE GROWTH FACTOR: NEUROTROPHIN OR CYTOKINE?
  in International archives of allergy and immunology
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Bonini S., Rasi G., Bracci-Laudiero M.L., Procoli A., Aloe L. (literal)

Pagina inizio

• 80 (literal)

Pagina fine

• 84 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 131/2 (literal)

Rivista

• International archives of allergy and immunology (Rivista)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Institute of Neurobiology and Molecular Medicine, Rome, Italy (literal)

Titolo

• NERVE GROWTH FACTOR: NEUROTROPHIN OR CYTOKINE? (literal)

Abstract

• Nerve growth factor (NGF) is a neutrophin exerting an important role in the development and functions of the central and peripheral nervous system. However, it has recently been documented that several immune cells - such as mast cells, lymphocytes and eosinophils - produce, store and release NGF. Moreover, NGF high and low affinity receptors are widely expressed in the immune system, thus indicating the potential of responding to this neurotrophin through an autocrine mechanism. In fact, NGF influences development differentiation, chemotaxis and mediator release of inflammatory cells as well as fibroblast activation through a complex network influenced by other pro-inflammatory cytokines. Finally, NGF is increased in biological fluids of several allergic, immune and inflammatory diseases. Data reviewed suggest, therefore, that NGF might also be viewed as a (Th2?) cytokine with a modulatory role in allergic inflammation and tissue remodeling. (literal)

Prodotto di

• Istituto di neurobiologia e medicina molecolare (INMM) (Istituto)
• Patologie infettive, infiammatorie e degenerative (ME.P04.005.001) (Modulo)

Autore CNR

• GUIDO RASI (Persona)
• LUIGI ALOE (Unità di personale interno)
• LUISA BRACCI LAUDIERO (Unità di personale interno)

Incoming links:

Autore CNR di

• GUIDO RASI (Persona)
• LUISA BRACCI LAUDIERO (Unità di personale interno)
• LUIGI ALOE (Unità di personale interno)

Prodotto

• Istituto di neurobiologia e medicina molecolare (INMM) (Istituto)
• Patologie infettive, infiammatorie e degenerative (ME.P04.005.001) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• International archives of allergy and immunology (Rivista)