Sr-substituted hydroxyapatites for osteoporotic bone replacement (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• Sr-substituted hydroxyapatites for osteoporotic bone replacement (Articolo in rivista) (literal)

Anno

• 2007-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1016/j.actbio.2007.05.006 (literal)

Alternative label

• Elena Landi; Anna Tampieri; Giancarlo Celotti; Simone Sprio; Monica Sandri; Giandomenico Logroscino (2007)
  Sr-substituted hydroxyapatites for osteoporotic bone replacement
  in Acta biomaterialia
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Elena Landi; Anna Tampieri; Giancarlo Celotti; Simone Sprio; Monica Sandri; Giandomenico Logroscino (literal)

Pagina inizio

• 961 (literal)

Pagina fine

• 969 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#url

• http://www.sciencedirect.com/science/article/pii/S1742706107000839 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 3 (literal)

Rivista

• Acta biomaterialia (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 6 (literal)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• ISTEC-CNR, Institute of Science and Technology for Ceramics, National Research Council, via Granarolo 64, 48018 Faenza (RA), Italy Orthopaedic Department, Catholic University of Rome, largo F.Vito, 1, 00168 Rome, Italy (literal)

Titolo

• Sr-substituted hydroxyapatites for osteoporotic bone replacement (literal)

Abstract

• Porous apatites, which during resorption can release in situ Sr ions, were prepared to associate an anti-osteoporotic action with the peculiar features of the inorganic phase constituting the bone. Sr-substituted hydroxyapatite (SrHA) powder was directly synthesized using the classical neutralization route, but including Sr ions, and characterized. The higher solubility of SrHA granules of 400-600 ?m size, potentially usable as a bone filler, was assessed compared with that of analogous stoichiometric HA granules. The Sr released in synthetic body fluid became constant after 1 week. The Ca release is improved for SrHA compared with stoichiometric HA, due to the higher solubility of the first material. Porous scaffolds with micro-macro interconnected porosity, which mimic the morphology of the spongy bone, were prepared by the impregnation of cellulose sponges with suspensions of the powder and a specific sintering process. A compressive strength of 4.52 ± 1.40 MPa was obtained for SrHA scaffolds characterized with 45 vol.% of porosity. Promising biomedical applications, such as resorbable bone filler or bone substitute releasing in situ Sr ions for a prolonged time, can be hypothesized for the SrHA materials when pathologies related with Sr deficiency are present. (literal)

Prodotto di

• Processi biomorfici e sviluppo di materiali biomimetici ad elevate performance bio-meccaniche per applicazioni in ingegneria tessutale (ME.P06.018.002) (Modulo)
• Institute of science and technology for ceramics (ISTEC) (Istituto)

Autore CNR

• GIANCARLO CELOTTI (Unità di personale interno)
• ANNA TAMPIERI (Persona)
• MONICA SANDRI (Persona)
• SIMONE SPRIO (Unità di personale interno)
• ELENA LANDI (Persona)

Insieme di parole chiave

• Parole chiave di "Sr-substituted hydroxyapatites for osteoporotic bone replacement" (Insieme di parole chiave)

Incoming links:

Prodotto

• Institute of science and technology for ceramics (ISTEC) (Istituto)
• Processi biomorfici e sviluppo di materiali biomimetici ad elevate performance bio-meccaniche per applicazioni in ingegneria tessutale (ME.P06.018.002) (Modulo)

Autore CNR di

• ANNA TAMPIERI (Persona)
• MONICA SANDRI (Persona)
• SIMONE SPRIO (Unità di personale interno)
• ELENA LANDI (Persona)
• GIANCARLO CELOTTI (Unità di personale interno)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Acta biomaterialia (Rivista)

Insieme di parole chiave di

• Parole chiave di "Sr-substituted hydroxyapatites for osteoporotic bone replacement" (Insieme di parole chiave)