Protein adsorption onto two bioactive glass-ceramics (Articolo in rivista)

Type
Label
  • Protein adsorption onto two bioactive glass-ceramics (Articolo in rivista) (literal)
Anno
  • 2003-01-01T00:00:00+01:00 (literal)
Alternative label
  • Rosengren A. , Oscarsson S. , Mazzocchi M. , Krajewski A. , Ravaglioli A. (2003)
    Protein adsorption onto two bioactive glass-ceramics
    in Biomaterials
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Rosengren A. , Oscarsson S. , Mazzocchi M. , Krajewski A. , Ravaglioli A. (literal)
Pagina inizio
  • 147 (literal)
Pagina fine
  • 155 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 24 (literal)
Rivista
Note
  • ISI Web of Science (WOS) (literal)
Titolo
  • Protein adsorption onto two bioactive glass-ceramics (literal)
Abstract
  • recent research suggest that the biocompatibility of an implant is to a large extent determined by selective adsorption of proteins from surrounding body fluids. Protein adsorption from human plasma onto two bioactive glass-ceramics (RKKP and AP40) which differ in La and Ta content, was studied by means of chromatography and two-dimensional polyacrylamaide gel electrophoresis (2D-PAGE). The quanmtitative analysis showed that the glass-ceramics have good protein binding capacities indicating multilayer formation. A correlation between chemica composition and the amount of adsorbed proteins was observed. The presence of La and Ta decreased the protein adsorption, so AP40 bound significantly more protein per surface unit than RKKP did. Preferential adsorption of alipoprotein J, fibrinogen and fibronectin was observed. (literal)
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