Human fibroblasts and 900 MHz RF radiation: evaluation of DNA damage after exposure and co-exposure to 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5h)-furanone (MX) (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Human fibroblasts and 900 MHz RF radiation: evaluation of DNA damage after exposure and co-exposure to 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5h)-furanone (MX) (Articolo in rivista) (literal)

Anno

• 2009-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1667/RR1642.1 (literal)

Alternative label

• Sannino A; Di Costanzo G; Brescia F; Sarti M; Zeni O; Juutilainen J; Scarfì MR; (2009)
  Human fibroblasts and 900 MHz RF radiation: evaluation of DNA damage after exposure and co-exposure to 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5h)-furanone (MX)
  in Radiation research
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Sannino A; Di Costanzo G; Brescia F; Sarti M; Zeni O; Juutilainen J; Scarfì MR; (literal)

Pagina inizio

• 743 (literal)

Pagina fine

• 751 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#url

• http://www.bioone.org/doi/abs/10.1667/RR1642.1 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 171 (literal)

Rivista

• Radiation research (Rivista)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• CNR, Inst Electromagnet Sensing Environm, Interuniv Ctr Interact Electromagnet Fields & Bio, I-80124 Naples, Italy CNR, Inst Electromagnet Sensing Environm, Interuniv Ctr Interact Electromagnet Fields & Bio, I-80124 Naples, Italy CNR, Inst Electromagnet Sensing Environm, Interuniv Ctr Interact Electromagnet Fields & Bio, I-80124 Naples, Italy CNR, Inst Electromagnet Sensing Environm, Interuniv Ctr Interact Electromagnet Fields & Bio, I-80124 Naples, Italy CNR, Inst Electromagnet Sensing Environm, Interuniv Ctr Interact Electromagnet Fields & Bio, I-80124 Naples, Italy Univ Kuopio, Dept Environm Sci, FIN-70211 Kuopio, Finland CNR, Inst Electromagnet Sensing Environm, Interuniv Ctr Interact Electromagnet Fields & Bio, I-80124 Naples, Italy (literal)

Titolo

• Human fibroblasts and 900 MHz RF radiation: evaluation of DNA damage after exposure and co-exposure to 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5h)-furanone (MX) (literal)

Abstract

• The aim of this study was to investigate DNA damage in human dermal fibroblasts from a healthy subject and from a subject affected by Turner's syndrome that were exposed for 24 h to radiofrequency (RF) radiation at 900 MHz. The RF-radiation exposure was carried out alone or in combination with 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX), a well-known environmental mutagen and carcinogen produced during the chlorination of drinking water. Turner's syndrome fibroblasts were also exposed for a shorter time (1 h). A signal similar to that emitted by Global System for Mobile Communications (GSM) mobile phones was used at a specific absorption rate of 1 W/kg under strictly controlled conditions of temperature and dosimetry. To evaluate DNA damage after RF-radiation exposure alone, the alkaline comet assay and the cytokinesis-block micronucleus assay were used. In the combined-exposure experiments, MX was given at a concentration of 25 mu M for 1 h immediately after the RF-radiation exposure, and the effects were evaluated by the alkaline comet assay. The results revealed no genotoxic and cytotoxic effects from RF radiation alone in either cell line. As expected, MX treatment induced an increase in DNA migration in the comet assay, but no enhancement of the MX-induced DNA damage was observed in the cells exposed to RF radiation. (literal)

Prodotto di

• Istituto per il rilevamento elettromagnetico dell'ambiente (IREA) (Istituto)
• Sicurezza e Compatibilità Elettromagnetica (ICT.P07.007.003) (Modulo)

Autore CNR

• MAURIZIO SARTI (Unità di personale interno)
• FRANCESCA BRESCIA (Persona)
• OLGA ZENI (Persona)
• ANNA SANNINO (Persona)
• MARIA ROSARIA SCARFI' (Unità di personale interno)

Insieme di parole chiave

• Keywords of "Human fibroblasts and 900 MHz RF radiation: evaluation of DNA damage after exposure and co-exposure to 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5h)-furanone (MX)" (Insieme di parole chiave)

Incoming links:

Autore CNR di

• MAURIZIO SARTI (Unità di personale interno)
• OLGA ZENI (Persona)
• MARIA ROSARIA SCARFI' (Unità di personale interno)
• ANNA SANNINO (Persona)
• FRANCESCA BRESCIA (Persona)

Prodotto

• Istituto per il rilevamento elettromagnetico dell'ambiente (IREA) (Istituto)
• Sicurezza e Compatibilità Elettromagnetica (ICT.P07.007.003) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Radiation research (Rivista)

Insieme di parole chiave di

• Keywords of "Human fibroblasts and 900 MHz RF radiation: evaluation of DNA damage after exposure and co-exposure to 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5h)-furanone (MX)" (Insieme di parole chiave)