http://www.cnr.it/ontology/cnr/individuo/prodotto/ID42945

Evaluation of genotoxic effects in human peripheral blood leukocytes following an acute in vitro exposure to 900 MHz radiofrequency fields (Articolo in rivista)

Type

Prodotto della ricerca (Classe)
Articolo in rivista (Classe)

Label

Evaluation of genotoxic effects in human peripheral blood leukocytes following an acute in vitro exposure to 900 MHz radiofrequency fields (Articolo in rivista) (literal)

Anno

2005-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

10.1002/bem.20078 (literal)

Alternative label

Zeni O., Romano' M., Perrotta A., Lioi M.B., Barbieri R., d'Ambrosio G., Massa R., Scarfi' M.R. (2005)
Evaluation of genotoxic effects in human peripheral blood leukocytes following an acute in vitro exposure to 900 MHz radiofrequency fields
in Bioelectromagnetics (Online); WILEY-LISS, DIV JOHN WILEY & SONS INC, 111 RIVER ST, HOBOKEN, NJ 07030 (Stati Uniti d'America)
(literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

Zeni O., Romano' M., Perrotta A., Lioi M.B., Barbieri R., d'Ambrosio G., Massa R., Scarfi' M.R. (literal)

Pagina inizio

258 (literal)

Pagina fine

265 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#url

http://onlinelibrary.wiley.com/journal/10.1002/%28ISSN%291521-186X (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

26 (literal)

Rivista

Bioelectromagnetics (Rivista)

Note

PubMe (literal)
ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

Olga Zeni, Maria Romano', Alessandro Perrotta and Maria Rosaria Scarfi'are with the Interuniversity Center on Interaction Between Electromagnetic Fields and Biosystems (ICEmB) at CNR-IREA, Naples, Italy Maria Brigida Lioi and Rocchina Barbieri are with the Department of Animal Science, University of Basilicata, Potenza, Italy Guglielmo dAmbrosio and Rita Massa are with the Department of Electronic Engineering and Telecommunications, University Federico II, Naples, Italy (literal)

Titolo

Evaluation of genotoxic effects in human peripheral blood leukocytes following an acute in vitro exposure to 900 MHz radiofrequency fields (literal)

Abstract

Human peripheral blood leukocytes from healthy volunteers have been employed to investigate the induction of genotoxic effects following 2 h exposure to 900MHz radiofrequency radiation. TheGSM signal has been studied at specific absorption rates (SAR) of 0.3 and 1 W/kg. The exposures were carried out in a waveguide system under strictly controlled conditions of both dosimetry and temperature. The same temperature conditions (37.0 0.1 8C) were realized in a second waveguide, employed to perform sham exposures. The induction of DNA damage was evaluated in leukocytes by applying the alkaline single cell gel electrophoresis (SCGE)/comet assay, while structural chromosome aberrations and sister chromatid exchanges were evaluated in lymphocytes stimulated with phytohemagglutinin. Alterations in kinetics of cell proliferation were determined by calculating the mitotic index. Positive controls were also provided by using methyl methanesulfonate (MMS) for comet assay and mitomycin-C (MMC), for chromosome aberration, or sister chromatid exchange tests. No statistically significant differences were detected in exposed samples in comparison with sham exposed ones for all the parameters investigated. On the contrary, the positive controls gave a statistically significant increase in DNA damage in all cases, as expected. Thus the results obtained in our experimental conditions do not support the hypothesis that 900 MHz radiofrequency field exposure induces DNA damage in human peripheral blood leukocytes in this range of SAR. (literal)

Editore