Native beta-lactoglobulin self-assembles into a hexagonal columnar phase on a solid surface (Articolo in rivista)

Type
Label
  • Native beta-lactoglobulin self-assembles into a hexagonal columnar phase on a solid surface (Articolo in rivista) (literal)
Anno
  • 2010-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1021/la902464f (literal)
Alternative label
  • B. Rizzuti, B. Zappone, M. P. De Santo, R. Guzzi (2010)
    Native beta-lactoglobulin self-assembles into a hexagonal columnar phase on a solid surface
    in Langmuir
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • B. Rizzuti, B. Zappone, M. P. De Santo, R. Guzzi (literal)
Pagina inizio
  • 1090 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#url
  • http://pubs.acs.org/doi/abs/10.1021/la902464f (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 26 (literal)
Rivista
Note
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • IPCF CS Univ della Calabria Dip. di Fisica (literal)
Titolo
  • Native beta-lactoglobulin self-assembles into a hexagonal columnar phase on a solid surface (literal)
Abstract
  • Using electron scanning microscopy, we have studied the protein deposit left on silicon and mica substrates by dried droplets of aqueous solutions of bovine ?-lactoglobulin at low concentration and pH = 2-7. We have observed different self-assembled structures: homogeneous layers, hexagonal platelets and flower-shaped patterns laying flat on thesurface,androdsformedbycolumns.Homogeneouslayerscoveredthelargestareaofthedropletdeposit.Theother structures were found in small isolated regions, where the protein solution dried in the form of microdroplets. The presence ofhexagonalplatelets, flower-shaped patterns andcolumnar rods shows that?-lactoglobulinself-assembles at the surface in a hexagonal columnar phase, which has never been observed in solution. A comparison with proteins showing similar aggregates suggests that ?-lactoglobulin structures grow from hexagonal germs composed of discotic nanometric building blocks, possibly possessing an octameric structure. We propose that discotic building blocks of ?- lactoglobulin may be produced by the anisotropic interaction with the solid surface. (literal)
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