Effects of voluntary ethanol consumption on emotional state and stress responsiveness in socially isolated rats. (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Effects of voluntary ethanol consumption on emotional state and stress responsiveness in socially isolated rats. (Articolo in rivista) (literal)

Anno

• 2011-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1016/j.euroneuro.2010.07.006 (literal)

Alternative label

• Pisu M.G., Mostallino M.C., Dore R., Maciocco E., Secci P.P., Serra M (2011)
  Effects of voluntary ethanol consumption on emotional state and stress responsiveness in socially isolated rats.
  in European neuropsychopharmacology
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Pisu M.G., Mostallino M.C., Dore R., Maciocco E., Secci P.P., Serra M (literal)

Pagina inizio

• 414 (literal)

Pagina fine

• 425 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#url

• http://www.sciencedirect.com (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 21 (literal)

Rivista

• European neuropsychopharmacology (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali

• 12 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 4 (literal)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• a Department of Experimental Biology, University of Cagliari, Cagliari 09100, Italy; b Center of Excellence for Neurobiology of Dependence, University of Cagliari, Cagliari 09100, Italy; c C.N.R., Institute of Neuroscience, Cagliari 09100, Italy (literal)

Titolo

• Effects of voluntary ethanol consumption on emotional state and stress responsiveness in socially isolated rats. (literal)

Abstract

• Social isolation of rats immediately after weaning is thought to represent an animal model of anxiety-like disorders. This mildly stressful condition reduces the cerebrocortical and plasma concentrations of 3?-hydroxy-5?-pregnan-20-one (3?,5?-TH PROG) as well as increases the sensitivity of rats to the effects of acute ethanol administration on the concentrations of this neuroactive steroid. We further investigated the effects of voluntary consumption of ethanol at concentrations increasing from 2.5 to 10% over 4 weeks of isolation. Isolated rats showed a reduced ethanol preference compared with group-housed animals. Ethanol consumption did not affect the isolation-induced down-regulation of BDNF or Arc, but it attenuated the increase in the cerebrocortical concentration of 3?,5?-TH PROG induced by foot-shock stress in both isolated and group-housed animals as well as increased the percentage of number of entries made by socially isolated rats into the open arms in the elevated plus-maze test. Ethanol consumption did not affect expression of the ?4 subunit of the GABAA receptor in the hippocampus of group-housed or isolated rats, whereas it up-regulated the ? subunit throughout the hippocampus under both conditions. The results suggest that low consumption of ethanol may ameliorate some negative effects of social isolation on stress sensitivity and behavior. (literal)

Prodotto di

• Neurobiologia delle dipendenze (ME.P02.009.001) (Modulo)
• Istituto di neuroscienze (IN) (Istituto)

Autore CNR

• MARIA ANGELA SERRA (Unità di personale esterno)
• MARIA CRISTINA MOSTALLINO (Persona)
• MARIA GIUSEPPINA PISU (Unità di personale interno)
• ELISABETTA MACIOCCO (Unità di personale interno)

Insieme di parole chiave

• Parole chiave di "Effects of voluntary ethanol consumption on emotional state and stress responsiveness in socially isolated rats." (Insieme di parole chiave)

Incoming links:

Autore CNR di

• MARIA GIUSEPPINA PISU (Unità di personale interno)
• MARIA CRISTINA MOSTALLINO (Persona)
• ELISABETTA MACIOCCO (Unità di personale interno)
• MARIA ANGELA SERRA (Unità di personale esterno)

Prodotto

• Istituto di neuroscienze (IN) (Istituto)
• Neurobiologia delle dipendenze (ME.P02.009.001) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• European neuropsychopharmacology (Rivista)

Insieme di parole chiave di

• Parole chiave di "Effects of voluntary ethanol consumption on emotional state and stress responsiveness in socially isolated rats." (Insieme di parole chiave)