Stable expression and functional characterization of a human nicotinic acetylcholine receptor with alpha 6 beta 2 properties: discovery of selective antagonists (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• Stable expression and functional characterization of a human nicotinic acetylcholine receptor with alpha 6 beta 2 properties: discovery of selective antagonists (Articolo in rivista) (literal)

Anno

• 2011-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1111/j.1476-5381.2011.01213.x (literal)

Alternative label

• Capelli, Anna Maria; Castelletti, Laura; Chen, Yu Hua; Van der Keyl, Harjeet; Pucci, Luca; Oliosi, Beatrice; Salvagno, Cristian; Bertani, Barbara; Gotti, Cecilia; Powell, Andrew; Mugnaini, Manolo (2011)
  Stable expression and functional characterization of a human nicotinic acetylcholine receptor with alpha 6 beta 2 properties: discovery of selective antagonists
  in British journal of pharmacology
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Capelli, Anna Maria; Castelletti, Laura; Chen, Yu Hua; Van der Keyl, Harjeet; Pucci, Luca; Oliosi, Beatrice; Salvagno, Cristian; Bertani, Barbara; Gotti, Cecilia; Powell, Andrew; Mugnaini, Manolo (literal)

Pagina inizio

• 313 (literal)

Pagina fine

• 329 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 163 (literal)

Rivista

• British journal of pharmacology (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali

• 17 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 2 (literal)

Note

• ISI Web of Science (WOS) (literal)
• ISI Web of Science (WoS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• GlaxoSmithKline; GlaxoSmithKline; GlaxoSmithKline; Consiglio Nazionale delle Ricerche (CNR) (literal)

Titolo

• Stable expression and functional characterization of a human nicotinic acetylcholine receptor with alpha 6 beta 2 properties: discovery of selective antagonists (literal)

Abstract

• Despite growing evidence that inhibition of alpha 6 beta 2-containing (alpha 6 beta 2*) nicotinic acetylcholine receptors (nAChRs) may be beneficial for the therapy of tobacco addiction, the lack of good sources of alpha 6 beta 2*-nAChRs has delayed the discovery of alpha 6 beta 2-selective antagonists. Our aim was to generate a cell line stably expressing functional nAChRs with alpha 6 beta 2 properties, to enable pharmacological characterization and the identification of novel alpha 6 beta 2-selective antagonists. (literal)
• BACKGROUND AND PURPOSE (literal)

Prodotto di

• Istituto di neuroscienze (IN) (Istituto)
• Farmacologia Cellulare e Molecolare delle Cellule Nervose (ME.P02.007.001) (Modulo)

Autore CNR

• CECILIA GOTTI (Persona)

Insieme di parole chiave

• Parole chiave di "Stable expression and functional characterization of a human nicotinic acetylcholine receptor with alpha 6 beta 2 properties: discovery of selective antagonists" (Insieme di parole chiave)

Incoming links:

Prodotto

• Istituto di neuroscienze (IN) (Istituto)
• Farmacologia Cellulare e Molecolare delle Cellule Nervose (ME.P02.007.001) (Modulo)

Autore CNR di

• CECILIA GOTTI (Persona)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• British journal of pharmacology (Rivista)

Insieme di parole chiave di

• Parole chiave di "Stable expression and functional characterization of a human nicotinic acetylcholine receptor with alpha 6 beta 2 properties: discovery of selective antagonists" (Insieme di parole chiave)