Changes in neuroactive steroid content during social isolation stress modulate GABA(A) receptor plasticity and function (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• Changes in neuroactive steroid content during social isolation stress modulate GABA(A) receptor plasticity and function (Articolo in rivista) (literal)

Anno

• 2008-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1016/j.brainresrev.2007.06.029 (literal)

Alternative label

• Serra M., Pisu M.G., Mostallino M.C., Sanna E., Biggio G (2008)
  Changes in neuroactive steroid content during social isolation stress modulate GABA(A) receptor plasticity and function
  in Brain research reviews
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Serra M., Pisu M.G., Mostallino M.C., Sanna E., Biggio G (literal)

Pagina inizio

• 520 (literal)

Pagina fine

• 530 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#url

• http://www.sciencedirect.com/ (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 57 (literal)

Rivista

• Brain research reviews (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali

• 11 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 2 (literal)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• aDepartment of Experimental Biology, Center of Excellence for the Neurobiology of Dependence, University of Cagliari, Cagliari, Italy; bC.N.R. Institute of Neuroscience, Italy (literal)

Titolo

• Changes in neuroactive steroid content during social isolation stress modulate GABA(A) receptor plasticity and function (literal)

Abstract

• Rats deprived of social contact with other rats at a young age experience a form of prolonged stress that leads to long-lasting alteration in their behavior profile. This chronic stress paradigm is thus thought to be anxiogenic for these normally gregarious animals and their abnormal reactivity to environmental stimuli, when reared under this condition, is thought to be a product of prolonged stress. Neurochemical, molecular, and electrophysiological evidences demonstrate that social isolation is associated with alteration in the structure and function of GABA(A) receptors and suggest that endogenous content of the progesterone metabolite 3alpha,5alpha-TH PROG may be an important determinant in regulating brain excitability and sensitivity to stimuli and point out its possible role in psychiatric and neurological disorder. (literal)

Prodotto di

• Istituto di neuroscienze (IN) (Istituto)
• Neurobiologia delle dipendenze (ME.P02.009.001) (Modulo)

Autore CNR

• GIOVANNI BIGGIO (Unità di personale esterno)
• MARIA ANGELA SERRA (Unità di personale esterno)
• MARIA GIUSEPPINA PISU (Unità di personale interno)
• MARIA CRISTINA MOSTALLINO (Persona)

Insieme di parole chiave

• Keywords of "Changes in neuroactive steroid content during social isolation stress modulate GABA(A) receptor plasticity and function" (Insieme di parole chiave)

Incoming links:

Autore CNR di

• MARIA GIUSEPPINA PISU (Unità di personale interno)
• MARIA CRISTINA MOSTALLINO (Persona)
• GIOVANNI BIGGIO (Unità di personale esterno)
• MARIA ANGELA SERRA (Unità di personale esterno)

Prodotto

• Istituto di neuroscienze (IN) (Istituto)
• Neurobiologia delle dipendenze (ME.P02.009.001) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Brain research reviews (Rivista)

Insieme di parole chiave di

• Keywords of "Changes in neuroactive steroid content during social isolation stress modulate GABA(A) receptor plasticity and function" (Insieme di parole chiave)