The mitochondrial permeability transition from in vitro artifact to disease target. (Articolo in rivista)

Type
Label
  • The mitochondrial permeability transition from in vitro artifact to disease target. (Articolo in rivista) (literal)
Anno
  • 2006-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1111/j.1742-4658.2006.05213.x (literal)
Alternative label
  • Bernardi P.; Krauskopf A.; Basso E.; Petronilli V.; Blachly-Dyson E.; Di Lisa F.; Forte M.A. (2006)
    The mitochondrial permeability transition from in vitro artifact to disease target.
    in The FEBS journal (Print)
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Bernardi P.; Krauskopf A.; Basso E.; Petronilli V.; Blachly-Dyson E.; Di Lisa F.; Forte M.A. (literal)
Pagina inizio
  • 2077 (literal)
Pagina fine
  • 2099 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 273 (literal)
Rivista
Note
  • ISI Web of Science (WOS) (literal)
  • PubMe (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • CNR Institute of Neuroscience and Department of Biomedical Sciences, University of Padova, Italy; CNR Institute of Neuroscience and Department of Biological Chemistry, University of Padova, Italy; Vollum Institute, Oregon Health and Sciences University, Portland, Oregon, USA (literal)
Titolo
  • The mitochondrial permeability transition from in vitro artifact to disease target. (literal)
Abstract
  • The mitochondrial permeability transition pore is a high conductance channel whose opening leads to an increase of mitochondrial inner membrane permeability to solutes with molecular masses up to approximate to 1500 Da. In this review we trace the rise of the permeability transition pore from the status of in vitro artifact to that of effector mechanism of cell death. We then cover recent results based on genetic inactivation of putative permeability transition pore components, and discuss their meaning for our understanding of pore structure. Finally, we discuss evidence indicating that the permeability transition pore plays a role in pathophysiology, with specific emphasis on in vivo models of disease. Accession Number: WOS:000237180700001 (literal)
Prodotto di
Autore CNR
Insieme di parole chiave

Incoming links:


Autore CNR di
Prodotto
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi
Insieme di parole chiave di
data.CNR.it