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Fragility of complexity biophysical systems by neutron scattering (Articolo in rivista)

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Fragility of complexity biophysical systems by neutron scattering (Articolo in rivista) (literal)

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Magazu, S; Migliardo, F; Bellocco, E; Lagana, G; Mondelli, C (2006)
Fragility of complexity biophysical systems by neutron scattering
in Physica. B, Condensed matter (Print)
(literal)

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Univ Messina, Dipartimento Fis, I-98166 Messina, Italy; Univ Messina, Dipartimento Chim Organ & Biol, I-98166 Messina, Italy; CNR, INFM, OGG, F-38042 Grenoble, France; ILL, CRS, SOFT, F-38042 Grenoble 9, France (literal)

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Neutron scattering is an exceptional tool to investigate structural and dynamical properties of systems of biophysical interest, such as proteins, enzymes, lipids and sugars. Moreover, elastic neutron scattering enhances the investigation of atomic motions in hydrated proteins in a wide temperature range and on the picosecond timescale. Homologous disaccharides, such as trehalose, maltose and sucrose, are cryptobiotic substances, since they allow to many organisms to undergo in a 'suspended life' state, known as cryptobiosis in extreme environmental conditions. The present paper is aimed to discuss the fragility degree of disaccharides, as evaluated of the temperature dependence of the mean square displacement by elastic neutron scattering, in order to link this feature with their bioprotective functions. (c) 2006 Elsevier B.V. All rights reserved. (literal)

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