Effects of 3,4-methylendioxymethamphetamine (MDMA, “ecstasy”) on dopamine transmission in the nucleus accumbens shell and core (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Effects of 3,4-methylendioxymethamphetamine (MDMA, “ecstasy”) on dopamine transmission in the nucleus accumbens shell and core (Articolo in rivista) (literal)

Anno

• 2005-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1016/j.brainres.2005.07.002 (literal)

Alternative label

• Cadoni C., Solinas M., Pisanu A., Zernig G., Acquas E., Di Chiara G. (2005)
  Effects of 3,4-methylendioxymethamphetamine (MDMA, “ecstasy”) on dopamine transmission in the nucleus accumbens shell and core
  in Brain research
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Cadoni C., Solinas M., Pisanu A., Zernig G., Acquas E., Di Chiara G. (literal)

Pagina inizio

• 143 (literal)

Pagina fine

• 148 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 1055 (literal)

Rivista

• Brain research (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali

• 6 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 1-2 (literal)

Note

• Scopus (literal)
• ISI Web of Science (WOS) (literal)
• Google Scholar (literal)
• PubMe (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Cadoni C. CNR Institute of Neuroscience, Section of Cagliari, Cagliari, Italy; Centre of Excellence for Neurobiology of Addiction, University of Cagliari, Cagliari, Italy. Solinas M. Dept. of Toxicology, University of Cagliari, Cagliari, Italy; Present address: Laboratorie de Biologie et Physiologie Cellulaire, CNRS, University of Poitiers, France. Pisanu A. Dept. of Toxicology, University of Cagliari, Cagliari, Italy. Zernig G. Division of Neurochemistry, Dep. of Psychiatry, University of Innsbruck, Innsbruck, Austria. Acquas E. Dept. of Toxicology, University of Cagliari, Cagliari, Italy; Centre of Excellence for Neurobiology of Addiction, University of Cagliari, Cagliari, Italy. Di Chiara G. Dept. of Toxicology, University of Cagliari, Cagliari, Italy; Centre of Excellence for Neurobiology of Addiction, University of Cagliari, Cagliari, Italy; CNR Institute of Neuroscience, Section of Cagliari, Cagliari, Italy. (literal)

Titolo

• Effects of 3,4-methylendioxymethamphetamine (MDMA, “ecstasy”) on dopamine transmission in the nucleus accumbens shell and core (literal)

Abstract

• It is known that most of drugs abused by humans preferentially stimulate dopamine transmission in the shell subdivision of the nucleus accumbens as compared to the core. The aim of the present study was to evaluate whether this applies also to intravenous 3,4-methylendioxymethamphetamine (MDMA, \"ecstasy\") administered at doses that sustain self-administration behavior in rats. The effect of 0.32, 0.64, 1.0, 2.0 and 3.2 mg/kg i.v. of MDMA on dopamine transmission in the nucleus accumbens shell and core was studied in freely moving rats by means of dual probe microdialysis. MDMA dose-dependently stimulated dopamine transmission both in the shell and in the core but the increase in the shell was more pronounced compared to the core at doses of 0.64, 1.0 and 2.0 mg/kg. The increase of dialysate dopamine obtained after 0.32 mg/kg and after 3.2 mg/kg was not significantly different in the shell compared to the core of nucleus accumbens. This study extends to MDMA the property of other drugs of abuse to increase preferentially nucleus accumbens shell dopamine. (literal)

Prodotto di

• Neurobiologia delle dipendenze (ME.P02.009.001) (Modulo)
• Istituto di neuroscienze (IN) (Istituto)

Autore CNR

• GAETANO DI CHIARA (Unità di personale esterno)
• CRISTINA CADONI (Persona)

Insieme di parole chiave

• Keywords of "Effects of 3,4-methylendioxymethamphetamine (MDMA, “ecstasy”) on dopamine transmission in the nucleus accumbens shell and core" (Insieme di parole chiave)

Incoming links:

Prodotto

• Istituto di neuroscienze (IN) (Istituto)
• Neurobiologia delle dipendenze (ME.P02.009.001) (Modulo)

Autore CNR di

• CRISTINA CADONI (Persona)
• GAETANO DI CHIARA (Unità di personale esterno)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Brain research (Rivista)

Insieme di parole chiave di

• Keywords of "Effects of 3,4-methylendioxymethamphetamine (MDMA, “ecstasy”) on dopamine transmission in the nucleus accumbens shell and core" (Insieme di parole chiave)