Endogenous ?×-hydroxybutyric acid is in the rat, mouse and human gastrointestinal tract. (Articolo in rivista)

Type
Label
  • Endogenous ?×-hydroxybutyric acid is in the rat, mouse and human gastrointestinal tract. (Articolo in rivista) (literal)
Anno
  • 2003-01-01T00:00:00+01:00 (literal)
Alternative label
  • Tedeschi L. 1, Carai M.A.M. 2, Frison G. 1, Favretto D. 1, Colombo G. 3, Ferrara S.D. 1, Gessa G.L. 2,3 (2003)
    Endogenous ?×-hydroxybutyric acid is in the rat, mouse and human gastrointestinal tract.
    in Life sciences (1973)
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Tedeschi L. 1, Carai M.A.M. 2, Frison G. 1, Favretto D. 1, Colombo G. 3, Ferrara S.D. 1, Gessa G.L. 2,3 (literal)
Pagina inizio
  • 2481 (literal)
Pagina fine
  • 2488 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 72 (literal)
Rivista
Note
  • ISI Web of Science (WOS) (literal)
Titolo
  • Endogenous ?×-hydroxybutyric acid is in the rat, mouse and human gastrointestinal tract. (literal)
Abstract
  • By using Gas Chromatography-Mass Spectrometry high concentrations of endogenous gamma-hydroxybutyric acid (GHB) have been demonstrated in the rat and mouse gastrointestinal tract, including stomach, small intestine and colon-rectum. GHB concentrations were many folds higher than those present in the brain. High GHB concentrations have been also found in the human operatory specimen of sigmoid colon. Since GHB administration has been found to modify gastrointestinal motility via GABA(B) receptors, the present results suggest that endogenous GHB might be involved in the GABA(B) receptor-mediated control of gastrointestinal function. (literal)
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