http://www.cnr.it/ontology/cnr/individuo/prodotto/ID3738
Thermal fluctuations of DNA enclosed by glycerol-water glassy matrices: an elastic neutron scattering investigation (Articolo in rivista)
- Type
- Label
- Thermal fluctuations of DNA enclosed by glycerol-water glassy matrices: an elastic neutron scattering investigation (Articolo in rivista) (literal)
- Anno
- 2008-01-01T00:00:00+01:00 (literal)
- Alternative label
Cornicchi, E; Capponi, S; Marconi, M; Onori, G; Paciaroni, A (2008)
Thermal fluctuations of DNA enclosed by glycerol-water glassy matrices: an elastic neutron scattering investigation
in European biophysics journal
(literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- Cornicchi, E; Capponi, S; Marconi, M; Onori, G; Paciaroni, A (literal)
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- ISI Web of Science (WOS) (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
- \"[Cornicchi, E.] Univ Perugia, Dipartimento Fis, CEMIN, I-06123 Perugia, Italy; INFM, CRS SOFT, I-06123 Perugia, Italy; [Capponi, S.] UPV EHU, Fac Quim, Donostia Int Phys Ctr, San Sebastian 20080, Spain; [Capponi, S.] UPV EHU, Fac Quim, Dept Fis Mat, San Sebastian 20080, Spain (literal)
- Titolo
- Thermal fluctuations of DNA enclosed by glycerol-water glassy matrices: an elastic neutron scattering investigation (literal)
- Abstract
- Through elastic neutron scattering measurements, we investigated the thermal fluctuations of DNA enclosed by glycerol-water glassy matrices, at different levels of hydration, over the wide temperature range from 20 to 300 K. For all the samples, the extracted hydrogen mean square displacements (MSD) show a purely vibrational harmonic trend at very low temperatures, and a first onset of anharmonic dynamics above similar to 100 K. Such onset is consistent with the activation of DNA methyl group rotational motions. Then, at a certain temperature T-d, the MSD show a second onset of anharmonicity, which corresponds to the DNA dynamical transition. The T-d values vary as a function of the hydration degree of the environment. The crucial role of the solvent mobility to activate the DNA thermal fluctuations is proposed, together with a preferential hydration effect of the DNA phosphate groups. Finally, a comparison between the average mobility of homologous samples of DNA and the lysozyme protein is considered. (literal)
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