Genetic loci influencing kidney function and chronic kidney disease (Articolo in rivista)

Type
Label
  • Genetic loci influencing kidney function and chronic kidney disease (Articolo in rivista) (literal)
Anno
  • 2010-01-01T00:00:00+01:00 (literal)
Alternative label
  • Chambers et al (2010)
    Genetic loci influencing kidney function and chronic kidney disease
    in Nature genetics (Print)
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Chambers et al (literal)
Rivista
Note
  • ISI Web of Science (WOS) (literal)
Titolo
  • Genetic loci influencing kidney function and chronic kidney disease (literal)
Abstract
  • Using genome-wide association, we identify common variants at 2p12–p13, 6q26, 17q23 and 19q13 associated with serum creatinine, a marker of kidney function. Of these, rs10206899 (near NAT8, 2p12–p13) and rs4805834 (near SLC7A9, 19q13) were also associated with chronic kidney disease. Our findings provide insight into metabolic, solute and drug-transport pathways underlying susceptibility to chronic kidney disease (literal)
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