Inflammatory effects on human lung epithelial cells after exposure to diesel exhaust micron sub particles (PM1.0) and pollen allergens (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Inflammatory effects on human lung epithelial cells after exposure to diesel exhaust micron sub particles (PM1.0) and pollen allergens (Articolo in rivista) (literal)

Anno

• 2012-01-01T00:00:00+01:00 (literal)

Alternative label

• Mazzarella G. 1, Esposito V. 2, Bianco A. 3, Ferraraccio F. 4, Prati M.V. 5, Lucariello A. 2, Manente L. 2, Mezzogiorno A. 2, De Luca A. 2 (2012)
  Inflammatory effects on human lung epithelial cells after exposure to diesel exhaust micron sub particles (PM1.0) and pollen allergens
  in Environmental pollution (1987)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Mazzarella G. 1, Esposito V. 2, Bianco A. 3, Ferraraccio F. 4, Prati M.V. 5, Lucariello A. 2, Manente L. 2, Mezzogiorno A. 2, De Luca A. 2 (literal)

Pagina inizio

• 64 (literal)

Pagina fine

• 69 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 161 (literal)

Rivista

• Environmental pollution (Rivista)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• 1) Department of Cardio-Thoracic and Respiratory Sciences, Second University of Naples, Naples, Italy; 2) Department of Medicine and Public Health, Section of Human Anatomy, Second University of Naples, Naples, Italy; 3) Department of Health Sciences, University of Molise, Campobasso, Italy; 4) Department of Medicine and Public Health, Section of Pathologic Anatomy, Second University of Naples, Naples, Italy; 5) Istituto Motori, National Research Council (CNR), Naples, Italy. (literal)

Titolo

• Inflammatory effects on human lung epithelial cells after exposure to diesel exhaust micron sub particles (PM1.0) and pollen allergens (literal)

Abstract

• Asthma is currently defined as a chronic inflammatory disease of the airway. Several evidence indicate that vehicle emissions in cities is correlated with the allergic respiratory diseases. In the present study, we evaluated in the A549 cells the production and release of IL-4, IL-5 and IL-13 after treatment with sub-micron PM1.0 particles (PM1.0), Parietaria officinalis (ALL), and PM1.0 + ALL together. Our data demonstrated that PM1.0 + ALL together exhibited the greatest capacity to induce A549 cells to enhance the expression of IL-4 and IL-5 compared with the only PM1.0 or ALL treatment. Interestingly, IL-13 that is necessary for allergen-induced airway hyper responsiveness, is increased in cells treated with PM1.0 + ALL together, but is higher expressed when the cells are treated only with the allergen. Our data support the hypothesis that the urban environment damage the acinar lung units and activates cells of the immune system. (literal)

Prodotto di

• Misura e caratterizzazione delle emissioni inquinanti, regolamentate e non, e di gas ad effetto serra (ET.P02.019.002) (Modulo)
• Istituto motori (IM) (Istituto)

Autore CNR

• MARIA VITTORIA PRATI (Persona)

Insieme di parole chiave

• Keywords of "Inflammatory effects on human lung epithelial cells after exposure to diesel exhaust micron sub particles (PM1.0) and pollen allergens" (Insieme di parole chiave)

Incoming links:

Prodotto

• Istituto motori (IM) (Istituto)
• Misura e caratterizzazione delle emissioni inquinanti, regolamentate e non, e di gas ad effetto serra (ET.P02.019.002) (Modulo)

Autore CNR di

• MARIA VITTORIA PRATI (Persona)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Environmental pollution (Rivista)

Insieme di parole chiave di

• Keywords of "Inflammatory effects on human lung epithelial cells after exposure to diesel exhaust micron sub particles (PM1.0) and pollen allergens" (Insieme di parole chiave)