Fabrication and characterization of a porous silicon based microarray for label-free optical monitoring of biomolecular interactions (Articolo in rivista)

Type
Label
  • Fabrication and characterization of a porous silicon based microarray for label-free optical monitoring of biomolecular interactions (Articolo in rivista) (literal)
Anno
  • 2010-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1063/1.3273410 (literal)
Alternative label
  • Rea I, Lamberti A, Rendina I, Coppola G, Gioffre M, Iodice M, Casalino M, De Tommasi E, De Stefano L (2010)
    Fabrication and characterization of a porous silicon based microarray for label-free optical monitoring of biomolecular interactions
    in Journal of applied physics
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Rea I, Lamberti A, Rendina I, Coppola G, Gioffre M, Iodice M, Casalino M, De Tommasi E, De Stefano L (literal)
Pagina inizio
  • 014513 (literal)
Pagina fine
  • 014513 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 107 (literal)
Rivista
Note
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • 1. CNR, Inst Microelect & Microsyst, Dept Naples, I-80131 Naples, Italy 2. Univ Naples Federico 2, Dept Biochem & Med Biotechnol, I-80131 Naples, Italy (literal)
Titolo
  • Fabrication and characterization of a porous silicon based microarray for label-free optical monitoring of biomolecular interactions (literal)
Abstract
  • We have fabricated a microarray of porous silicon Bragg reflectors on a crystalline silicon substrate using a technological process based on standard photolithography and electrochemical anodization of the silicon. The array density is of 170 elements/cm(2) and each element has a diameter of 200 mu m. The porous silicon structures have been used as platform to immobilize an amino terminated DNA single strand probe. All fabrication steps have been monitored by spectroscopic reflectometry, optical and electron microscopy, and Fourier transform infrared spectroscopy. A label-free detection method has been employed to investigate the hybridization between micromolar DNA probe and its complementary target. Due to fast and low cost production, good reproducibility, and high quality optical features, this platform could be adopted also for other different microarray applications such as proteomics and medical diagnostics. (literal)
Prodotto di
Autore CNR

Incoming links:


Prodotto
Autore CNR di
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi
data.CNR.it