http://www.cnr.it/ontology/cnr/individuo/prodotto/ID3568

A compact and disposable transdermal drug delivery system (Articolo in rivista)

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A compact and disposable transdermal drug delivery system (Articolo in rivista) (literal)

Anno

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Matteucci, M; Casella, M; Bedoni, M; Donetti, E; Fanetti, M; De Angelis, F; Gramatica, F; Di Fabrizio, E (2008)
A compact and disposable transdermal drug delivery system
in Microelectronic engineering
(literal)

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Matteucci, M; Casella, M; Bedoni, M; Donetti, E; Fanetti, M; De Angelis, F; Gramatica, F; Di Fabrizio, E (literal)

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\"[Matteucci, M.] Sincrotrone Trieste, I-34012 Basovizza Trieste, Italy; [Casella, M.; Bedoni, M.; Gramatica, F.] Fdn Don Gnocchi IRCCS ONLUS, Biophys & Nanomed Lab, I-20148 Milan, Italy; [Bedoni, M.; Donetti, E.] Univ Milan, I-20133 Milan, Italy; [Fanetti, M.] Univ Cattolica, CNR INFM, I-25121 Brescia, Italy; [Fanetti, M.] Univ Cattolica, Dipartimento Matemat & Fis, I-25121 Brescia, Italy; [Casella, M.; De Angelis, F.; Di Fabrizio, E.] Magna Graecia Univ Catanzaro, BIONEM Lab, Div Med Sperimentale & Clin, I-88100 Catanzaro, Italy; [Di Fabrizio, E.] INFM TASC SS, I-34012 Basovizza Trieste, Italy (literal)

Titolo

Abstract

This work presents a portable transdermal drug delivery system that combines a magnetically actuated micro gear pump with a microneedle array. Micropart fabrication is performed through DXRL and LIGA techniques. The manufacturing process of both micropump and microneedle array are described together with wear issues. Results show that the assembled device can deliver rates that go from 0.1 to 1.2 ml/min at gear speed ranging from 1000 to 8500 rpm. First skin piercing experiments are also described. (C) 2008 Elsevier B.V. All rights reserved. (literal)

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