The complex of hypericin with beta-lactoglobulin has antimicrobial activity with potential applications in dairy industry (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• The complex of hypericin with beta-lactoglobulin has antimicrobial activity with potential applications in dairy industry (Articolo in rivista) (literal)

Anno

• 2015-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.3168/jds.2014-8691 (literal)

Alternative label

• Rodriguez-Amigo, Beatriz; Delcanale, Pietro; Rotger, Gabriel; Juarez-Jimenez, Jordi; Abbruzzetti, Stefania; Summer, Andrea; Agut, Montserrat; Luque, Javier; Nonell, Santi; Viappiani, Cristiano (2015)
  The complex of hypericin with beta-lactoglobulin has antimicrobial activity with potential applications in dairy industry
  in Journal of dairy science
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Rodriguez-Amigo, Beatriz; Delcanale, Pietro; Rotger, Gabriel; Juarez-Jimenez, Jordi; Abbruzzetti, Stefania; Summer, Andrea; Agut, Montserrat; Luque, Javier; Nonell, Santi; Viappiani, Cristiano (literal)

Pagina inizio

• 89 (literal)

Pagina fine

• 94 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 98 (literal)

Rivista

• Journal of dairy science (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali

• 6 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 1 (literal)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• [ 1 ] Univ Ramon Llull, Inst Quim Sarria, Barcelona 08017, Spain [ 2 ] Univ Parma, Dipartimento Fis & Sci Terra, I-43124 Parma, Italy [ 3 ] Univ Barcelona, Fac Farm, Inst Biomed, Dept Quim Fis, Santa Coloma De Gramenet 08921, Spain [ 4 ] Univ Parma, Dept Biosci, I-43124 Parma, Italy [ 5 ] CNR, Ist Nanosci, NEST, I-56127 Pisa, Italy [ 6 ] Univ Parma, Dipartimento Sci Alimenti, I-43126 Parma, Italy (literal)

Titolo

• The complex of hypericin with beta-lactoglobulin has antimicrobial activity with potential applications in dairy industry (literal)

Abstract

• Using a combination of molecular modeling and spectroscopic experiments, the naturally occurring, pharmacologically active hypericin compound is shown to form a stable complex with the dimeric form of beta-lactoglobulin (beta-LG). Binding is predicted to occur at the narrowest cleft found at the interface between monomers in the dimeric beta-LG. The complex is able to preserve the fluorescence and singlet oxygen photosensitizing properties of the dye. The equilibrium constant for hypericin binding has been determined as K-a = 1.40 +/- 0.07 mu M-1, equivalent to a dissociation constant, K-d = 0.71 +/- 0.03 mu M. The complex is active against Staphylococcus aureus bacteria. Overall, the results are encouraging for pursuing the potential application of the complex between hypericin and beta-LG as a nanodevice with bactericidal properties for disinfection. (literal)

Prodotto di

• Progettazione ed applicazioni di Nanobiotecnologie (MD.P06.022.002) (Modulo)

Autore CNR

• CRISTIANO VIAPPIANI (Unità di personale esterno)

Insieme di parole chiave

• Parole chiave di "The complex of hypericin with beta-lactoglobulin has antimicrobial activity with potential applications in dairy industry" (Insieme di parole chiave)

Incoming links:

Autore CNR di

• CRISTIANO VIAPPIANI (Unità di personale esterno)
• http://www.cnr.it/ontology/cnr/individuo/unitaDiPersonaleEsterno/ID25140

Prodotto

• Progettazione ed applicazioni di Nanobiotecnologie (MD.P06.022.002) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Journal of dairy science (Rivista)

Insieme di parole chiave di

• Parole chiave di "The complex of hypericin with beta-lactoglobulin has antimicrobial activity with potential applications in dairy industry" (Insieme di parole chiave)