The multiple cellular functions of the oncoprotein Golgi phoshoprotein 3 (Articolo in rivista)

Type
Label
  • The multiple cellular functions of the oncoprotein Golgi phoshoprotein 3 (Articolo in rivista) (literal)
Anno
  • 2015-01-01T00:00:00+01:00 (literal)
Alternative label
  • Sechi S., Frappaolo A, Belloni G., Colotti G., Giansanti MG. (2015)
    The multiple cellular functions of the oncoprotein Golgi phoshoprotein 3
    in Oncotarget
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Sechi S., Frappaolo A, Belloni G., Colotti G., Giansanti MG. (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 6 (literal)
Rivista
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo
  • 6 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • Istituto di Biologia e Patologia Molecolari del CNR (literal)
Titolo
  • The multiple cellular functions of the oncoprotein Golgi phoshoprotein 3 (literal)
Abstract
  • The highly conserved Golgi phosphoprotein 3 (GOLPH3) protein, a component of Trans-Golgi Network (TGN), has been defined as a \"first-in-class Golgi oncoprotein\" and characterized as a Phosphatidylinositol 4-phosphate [PI(4)P] effector at the Golgi. GOLPH3 is commonly amplified in several solid tumors. Furthermore this protein has been associated with poor prognosis in many cancers. Highly conserved from yeast to humans, GOLPH3 provides an essential function in vesicle trafficking and Golgi structure. Recent data have also implicated this oncoprotein in regulation of cytokinesis, modulation of mitochondrial mass and cellular response to DNA damage. A minute dissection of the molecular pathways that require GOLPH3 protein will be helpful to develop new therapeutic cancer strategies. (literal)
Prodotto di
Autore CNR
Insieme di parole chiave

Incoming links:


Prodotto
Autore CNR di
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi
Insieme di parole chiave di
data.CNR.it