Cytotoxicity assessment of silica-based nanosized contrast agents for ultrasound molecular imaging (Contributo in atti di convegno)

Type

• Prodotto della ricerca (Classe)
• Contributo in atti di convegno (Classe)

Label

• Cytotoxicity assessment of silica-based nanosized contrast agents for ultrasound molecular imaging (Contributo in atti di convegno) (literal)

Anno

• 2011-01-01T00:00:00+01:00 (literal)

Alternative label

• Dipaola L., Chiriacò F., Sbenaglia E.A., Conversano F., Ragusa A., Casciaro S. (2011)
  Cytotoxicity assessment of silica-based nanosized contrast agents for ultrasound molecular imaging
  in 2011 IEEE Sensors, Limerick, Ireland, 28-31 Ottobre 2011
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Dipaola L., Chiriacò F., Sbenaglia E.A., Conversano F., Ragusa A., Casciaro S. (literal)

Pagina inizio

• 266 (literal)

Pagina fine

• 268 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#titoloVolume

• 2011 IEEE Sensors Proceedings (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali

• 3 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• National Research Council, Bioengineering Division, Institute of Clinical Physiology, Lecce, Italy; National Research Council, National Nanotechnology Laboratory CNR-NANO, Lecce, Italy (literal)

Titolo

• Cytotoxicity assessment of silica-based nanosized contrast agents for ultrasound molecular imaging (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#isbn

• 978-1-4244-9288-6 (literal)

Abstract

• Nanosized contrast agents for medical imaging are being increasingly studied because of their potential for direct and selective targeting of diseased cells located in the extravascular compartment. Recently, our research group has experimentally investigated the echogenicity of silica nanospheres (SiNSs), potentially useful for tumor targeting purposes, demonstrating their contrast enhancement power on conventional ultrasound (US) images in a wide range of sizes and concentrations. In the present work, we evaluated the \"in vitro\" cytotoxicity of SiNSs at variable concentration in human cervical cancer cell line (HeLa). Toxicity of SiNSs with diameter in our investigated range (160-330 nm) had never been previously quantified, although this is the most promising size interval for US targeted imaging. Our reported results indicated a SiNS concentration range which does not cause appreciable decrements in cell survival, being therefore safely exploitable for contrast-enhanced US imaging. (literal)

Prodotto di

• Nano imaging (ME.P01.015.003) (Modulo)
• Istituto di fisiologia clinica (IFC) (Istituto)

Autore CNR

• LUCIA DIPAOLA (Unità di personale interno)
• FRANCESCO CONVERSANO (Persona)
• ENZO ANTONIO SBENAGLIA (Unità di personale interno)
• SERGIO CASCIARO (Unità di personale interno)

Incoming links:

Prodotto

• Istituto di fisiologia clinica (IFC) (Istituto)
• Nano imaging (ME.P01.015.003) (Modulo)

Autore CNR di

• SERGIO CASCIARO (Unità di personale interno)
• LUCIA DIPAOLA (Unità di personale interno)
• FRANCESCO CONVERSANO (Persona)
• ENZO ANTONIO SBENAGLIA (Unità di personale interno)