http://www.cnr.it/ontology/cnr/individuo/prodotto/ID325571
In vitro ultrasound characterization of human proximal femur microstructure and comparison with micro-CT data (Contributo in atti di convegno)
- Type
- Label
- In vitro ultrasound characterization of human proximal femur microstructure and comparison with micro-CT data (Contributo in atti di convegno) (literal)
- Anno
- 2014-01-01T00:00:00+01:00 (literal)
- Alternative label
M. Peccarisi, T. De Marco, L. Spedicato, A. Greco, F. Conversano, D. Panetta, G. Guido, V. Bottai, P. Salvadori and S. Casciaro (2014)
In vitro ultrasound characterization of human proximal femur microstructure and comparison with micro-CT data
in 3rd Imeko TC13 Symposium on Measurements in Biology and Medicine "New Frontiers in Biomedical Measurements", Lecce, Italy, 17-18 Aprile 2014
(literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- M. Peccarisi, T. De Marco, L. Spedicato, A. Greco, F. Conversano, D. Panetta, G. Guido, V. Bottai, P. Salvadori and S. Casciaro (literal)
- Pagina inizio
- Pagina fine
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#titoloVolume
- Proceedings of the 3rd Imeko TC13 Symposium on Measurements in Biology and Medicine \"New Frontiers in Biomedical Measurements\" (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
- Echolight S.r.l., Lecce, Italy; National Research Council, Institute of Clinical Physiology, Lecce-Pisa, Italy; Clinica Ortopedica e Traumatologica II, University of Pisa, Pisa, Italy. (literal)
- Titolo
- In vitro ultrasound characterization of human proximal femur microstructure and comparison with micro-CT data (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#isbn
- 978-92-990073-5-8 (literal)
- Abstract
- An in vitro investigation based on Quantitative
Ultrasound (QUS) has been carried out in this paper on a
sample of human femoral head, aiming at microstructure
characterization and bone quality assessment. Two QUS
parameters, Integrated Reflection Coefficient (IRC) and
Apparent Integrated Backscatter (AIB) were measured by
accurately analyzing ultrasonic signals backscattered from
the target bone when immersed in water and insonified at
2.25 MHz. In particular, US data were acquired from 22
different positions along the maximum section
perpendicular to the axial direction (head-neck axis) of the
target sample. The obtained data were compared with local
structural properties gathered at each considered position
from a high-resolution micro-computed tomography
(microCT) scan of the same sample. A linear regression
analysis showed an appreciable correlation between QUS
parameters and some of the micro-structural parameters. As
expected, IRC correlated better with cortical bone volume
fraction (r = -0.53), and AIB with trabecular bone volume
fraction (r = -0.60) and trabecular spacing (r = 0.47). These
results are particularly encouraging in view of a possible
clinical translation of the proposed approach for early
osteoporosis diagnosis. (literal)
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