Diagnostic accuracy of a novel ultrasound-based methodology for spinal densitometry on a cohort of normal- and under-weight women (Contributo in atti di convegno)

Type
Label
  • Diagnostic accuracy of a novel ultrasound-based methodology for spinal densitometry on a cohort of normal- and under-weight women (Contributo in atti di convegno) (literal)
Anno
  • 2014-01-01T00:00:00+01:00 (literal)
Alternative label
  • M. D. Renna, F. Conversano, P. Pisani, E. Casciaro, L. Quarta, D. Costanza, M. Muratore and S. Casciaro (2014)
    Diagnostic accuracy of a novel ultrasound-based methodology for spinal densitometry on a cohort of normal- and under-weight women
    in 3rd Imeko TC13 Symposium on Measurements in Biology and Medicine "New Frontiers in Biomedical Measurements", Lecce, Italy, 17-18 Aprile 2014
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • M. D. Renna, F. Conversano, P. Pisani, E. Casciaro, L. Quarta, D. Costanza, M. Muratore and S. Casciaro (literal)
Pagina inizio
  • 40 (literal)
Pagina fine
  • 44 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#titoloVolume
  • Proceedings of the 3rd Imeko TC13 Symposium on Measurements in Biology and Medicine \"New Frontiers in Biomedical Measurements\" (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali
  • 5 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • National Research Council, Institute of Clinical Physiology, Lecce, Italy; O.U. of Rheumatology, \"Galateo\" Hospital, San Cesario di Lecce, ASL-LE, Lecce, Italy. (literal)
Titolo
  • Diagnostic accuracy of a novel ultrasound-based methodology for spinal densitometry on a cohort of normal- and under-weight women (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#isbn
  • 978-92-990073-5-8 (literal)
Abstract
  • Currently, osteoporosis is mainly diagnosed through dual-energy X-ray absorptiometry (DXA). However, DXA cannot be used for early diagnoses through population mass screenings because of issues related to ionizing radiation employment. This paper describes the diagnostic accuracy of a novel ultrasound (US)-based method to perform spinal densitometry without employing X-rays. The proposed innovative methodology is based on a combined analysis of both echographic images and \"raw\" radiofrequency US signals. The diagnostic output is represented by the same parameters of DXA (bone mineral density (BMD), T-score, Z-score). The actual effectiveness of the proposed methodology was evaluated on a cohort of 350 normal-weight or underweight (body mass index (BMI) < 25 kg/m2) female patients in the age range 45-65 years by a direct comparison with DXA assumed as gold standard. The accuracy of US-based diagnoses ranged from a maximum of 90.5% to a minimum of 74.1%, corresponding to the youngest and oldest patient age category, respectively, with an average of 84.9%. A good correlation was also found between US-estimated BMD and DXA related values (r=0.69, p<0.001). Obtained results demonstrated the high accuracy of the proposed US approach to spinal bone densitometry compared with DXA. This technique has the potential to become a useful and effective tool in clinical practice improving the current approach to osteoporosis diagnosis. (literal)
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