http://www.cnr.it/ontology/cnr/individuo/prodotto/ID325456
Diagnostic accuracy of a novel ultrasound-based methodology for spinal densitometry on a cohort of normal- and under-weight women (Contributo in atti di convegno)
- Type
- Label
- Diagnostic accuracy of a novel ultrasound-based methodology for spinal densitometry on a cohort of normal- and under-weight women (Contributo in atti di convegno) (literal)
- Anno
- 2014-01-01T00:00:00+01:00 (literal)
- Alternative label
M. D. Renna, F. Conversano, P. Pisani, E. Casciaro, L. Quarta, D. Costanza, M. Muratore and S. Casciaro (2014)
Diagnostic accuracy of a novel ultrasound-based methodology for spinal densitometry on a cohort of normal- and under-weight women
in 3rd Imeko TC13 Symposium on Measurements in Biology and Medicine "New Frontiers in Biomedical Measurements", Lecce, Italy, 17-18 Aprile 2014
(literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- M. D. Renna, F. Conversano, P. Pisani, E. Casciaro, L. Quarta, D. Costanza, M. Muratore and S. Casciaro (literal)
- Pagina inizio
- Pagina fine
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#titoloVolume
- Proceedings of the 3rd Imeko TC13 Symposium on Measurements in Biology and Medicine \"New Frontiers in Biomedical Measurements\" (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
- National Research Council, Institute of Clinical Physiology, Lecce, Italy; O.U. of Rheumatology, \"Galateo\" Hospital, San Cesario di Lecce, ASL-LE, Lecce, Italy. (literal)
- Titolo
- Diagnostic accuracy of a novel ultrasound-based methodology for spinal densitometry on a cohort of normal- and under-weight women (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#isbn
- 978-92-990073-5-8 (literal)
- Abstract
- Currently, osteoporosis is mainly diagnosed
through dual-energy X-ray absorptiometry (DXA). However,
DXA cannot be used for early diagnoses through population
mass screenings because of issues related to ionizing
radiation employment. This paper describes the diagnostic
accuracy of a novel ultrasound (US)-based method to
perform spinal densitometry without employing X-rays. The
proposed innovative methodology is based on a combined
analysis of both echographic images and \"raw\"
radiofrequency US signals. The diagnostic output is
represented by the same parameters of DXA (bone mineral
density (BMD), T-score, Z-score). The actual effectiveness
of the proposed methodology was evaluated on a cohort of
350 normal-weight or underweight (body mass index (BMI)
< 25 kg/m2) female patients in the age range 45-65 years by
a direct comparison with DXA assumed as gold standard.
The accuracy of US-based diagnoses ranged from a
maximum of 90.5% to a minimum of 74.1%, corresponding
to the youngest and oldest patient age category, respectively,
with an average of 84.9%. A good correlation was also
found between US-estimated BMD and DXA related values
(r=0.69, p<0.001). Obtained results demonstrated the high
accuracy of the proposed US approach to spinal bone
densitometry compared with DXA. This technique has the
potential to become a useful and effective tool in clinical
practice improving the current approach to osteoporosis
diagnosis. (literal)
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