http://www.cnr.it/ontology/cnr/individuo/prodotto/ID325441
Clinical evaluation of a novel ultrasound-based methodology for osteoporosis diagnosis on overweight and obese women (Contributo in atti di convegno)
- Type
- Label
- Clinical evaluation of a novel ultrasound-based methodology for osteoporosis diagnosis on overweight and obese women (Contributo in atti di convegno) (literal)
- Anno
- 2014-01-01T00:00:00+01:00 (literal)
- Alternative label
S. Casciaro, M. D. Renna, F. Conversano, G. Soloperto, E. Casciaro, E. Quarta, A. Grimaldi and M. Muratore (2014)
Clinical evaluation of a novel ultrasound-based methodology for osteoporosis diagnosis on overweight and obese women
in 3rd Imeko TC13 Symposium on Measurements in Biology and Medicine "New Frontiers in Biomedical Measurements", Lecce, Italy, 17-18 Aprile 2014
(literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- S. Casciaro, M. D. Renna, F. Conversano, G. Soloperto, E. Casciaro, E. Quarta, A. Grimaldi and M. Muratore (literal)
- Pagina inizio
- Pagina fine
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#titoloVolume
- Proceedings of the 3rd Imeko TC13 Symposium on Measurements in Biology and Medicine \"New Frontiers in Biomedical Measurements\" (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
- National Research Council, Institute of Clinical Physiology, Lecce, Italy; O.U. of Rheumatology, \"Galateo\" Hospital, San Cesario di Lecce, ASL-LE, Lecce, Italy. (literal)
- Titolo
- Clinical evaluation of a novel ultrasound-based methodology for osteoporosis diagnosis on overweight and obese women (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#isbn
- 978-92-990073-5-8 (literal)
- Abstract
- Osteoporosis and overweight/obesity
constitute major worldwide public health burdens that are
associated with aging. The gold standard for osteoporosis
diagnosis is currently represented by bone mineral density
(BMD) measurement through dual-energy X-ray
absorptiometry (DXA). However, DXA cannot be used for
early diagnosis through population mass screenings due to
ionizing radiation employment. Because of this, generally,
only people considered at high risk of fracture (underweight
women after the menopause) undergo to osteoporosis
screening. In fact, a significant risk factor for fracture is the
low body mass index (BMI), while the tendency to
overweight or obesity delays osteoporosis onset.
Nevertheless, a high proportion of women after the
menopause develop intra-abdominal adiposity, which leads
to metabolic disorders and osteoporosis. This paper
describes the diagnostic accuracy of a novel ultrasound
(US)-based method to perform spinal densitometry. The
proposed innovative methodology is based on a combined
analysis of both echographic images and \"raw\"
radiofrequency US signals. The diagnostic output is
represented by the same parameters provided by DXA
(BMD, T-score, Z-score). The efficiency of the proposed
methodology was evaluated on a cohort of 280 overweight
or obese (BMI > 25 kg/m2) female patients in the age range
45-65 years. For 81.4% of the patients, US diagnosis
(osteoporotic, osteopenic, healthy) was the same of the
corresponding DXA one, showing the high accuracy of the
proposed US technique, especially in the youngest patients
(86.4% of correct diagnoses in the age range 45-50 y). A
good correlation was also found between the diagnostic
parameters provided by both US and DXA methods: all
obtained values of Pearson coefficient (r) were within the
interval 0.66-0.76 (p<0.001). Then, this new non-ionizing
approach to spinal bone densitometry has the potential for
being extremely useful for early osteoporosis diagnosis
through population mass screenings. (literal)
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