Advances in asthma pathophysiology: stepping forward from the Maurizio Vignola experience. (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• Advances in asthma pathophysiology: stepping forward from the Maurizio Vignola experience. (Articolo in rivista) (literal)

Anno

• 2015-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1183/09059180.10011114 (literal)

Alternative label

• Maria R. Bonsignore1,2?, Mirella Profita2, Rosalia Gagliardo2, Loredana Riccobono2, Giuseppina Chiappara2, Elisabetta Pace2 and Mark Gjomarkaj2 (2015)
  Advances in asthma pathophysiology: stepping forward from the Maurizio Vignola experience.
  in European respiratory review
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Maria R. Bonsignore1,2?, Mirella Profita2, Rosalia Gagliardo2, Loredana Riccobono2, Giuseppina Chiappara2, Elisabetta Pace2 and Mark Gjomarkaj2 (literal)

Pagina inizio

• 30 (literal)

Pagina fine

• 39 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#altreInformazioni

• European respiratory review (Online) Attiva dal: 2005 Editore: European Respiratory Society - Lausanne Lingua: inglese Issn: 1600-0617 Titolo chiave: European respiratory review (Online) Titolo proprio: European respiratory review. (Online) Titolo abbreviato: Eur. respir. rev. (Online) ID: 97771 ,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, Acknowledgements More people than those directly contributing to this review article collaborated with Maurizio Vignola on asthma projects: Anna Bonanno, Andreina Bruno, Maria Ferraro, Stefania La Grutta, Mario Melis, Anna Merendino, Liboria Siena, Fabio Bucchieri, Laura Chimenti, Giorgia Costanzo, Rossana Di Giorgi, Francesca Guddo, Daniela Guerrera, Franco Mirabella, Alessandra Paternò, Aroldo Rizzo, Nicola Scichilone and Annalisa Tipa. Many of them still work at the CNR Institute of Biomedicine and Molecular Immunology or at the University of Palermo (both Palermo, Italy), and their contribution is acknowledged. Finally, a special acknowledgment is dedicated to Giovanni Bonsignore, Professor Emeritus of Respiratory Medicine (1927-2007), who introduced many young fellows, including Maurizio Vignola, to respiratory basic and clinical research. (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#url

• http://err.ersjournals.com (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 24 (literal)

Rivista

• European respiratory review (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali

• 9 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 135 (literal)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• 1 Biomedical Dept of Internal and Specialistic Medicine (DiBiMIS), Pneumology, University of Palermo, Palermo, Italy 2 Institute of Biomedicine and Molecular Immunology (IBIM), National Research Council (CNR), Palermo, Italy (literal)

Titolo

• Advances in asthma pathophysiology: stepping forward from the Maurizio Vignola experience. (literal)

Abstract

• Maurizio Vignola was a superb and innovative researcher, who wrote seminal papers on the biology of airway epithelium in asthma. Inflammation and remodelling were the main topics of his research, mostly conducted in biopsy specimens from patients with asthma of variable severity, encompassing the entire spectrum of the disease from mild to severe asthma. His observations contributed to define the biology of asthma as we know it today, and opened the way to the personalised treatment of asthma. His group has successfully continued to investigate the biology and clinical aspects of bronchial asthma, with major interest in the clinical use of biomarkers to monitor disease activity, and in the development of new therapeutic perspectives. This review summarises the latest work on these topics proudly conducted by Maurizio's closest collaborators. The results indicate significant progress in our understanding of asthma in the last 10 years, in particular increased knowledge of the complex interaction between inflammatory and remodelling pathways, improved recognition of biological and clinical asthma phenotypes, and development of new treatment strategies, especially for patients with severe corticosteroid-resistant asthma. (literal)

Prodotto di

• Immunopatologia e Farmacologia Clinica e Sperimentale nelle malattie respiratorie (ME.P01.014.005) (Modulo)
• Modelli ex vivo/in vitro per lo studio dell'immunopatologia e della farmacologia nelle pneumopatie (ME.P01.014.007) (Modulo)
• Istituto di biomedicina e di immunologia molecolare \"Alberto Monroy\" (IBIM) (Istituto)
• Immunopatologia e Farmacologia nelle Pneumopatie: studi dei meccanismi molecolari in vivo e in modelli in vitro (ME.P01.014.006) (Modulo)

Autore CNR

• ROSALIA PAOLA GAGLIARDO (Unità di personale interno)
• ELISABETTA PACE (Unità di personale interno)
• MIRELLA PROFITA (Unità di personale interno)
• GIUSEPPINA CHIAPPARA (Unità di personale interno)
• MARK GJOMARKAJ (Persona)
• MARIA ROSARIA BONSIGNORE (Unità di personale esterno)
• LOREDANA RICCOBONO (Persona)

Insieme di parole chiave

• Keywords of "Advances in asthma pathophysiology: stepping forward from the Maurizio Vignola experience." (Insieme di parole chiave)

Incoming links:

Autore CNR di

• MARK GJOMARKAJ (Persona)
• GIUSEPPINA CHIAPPARA (Unità di personale interno)
• LOREDANA RICCOBONO (Persona)
• ROSALIA PAOLA GAGLIARDO (Unità di personale interno)
• MIRELLA PROFITA (Unità di personale interno)
• ELISABETTA PACE (Unità di personale interno)
• MARIA ROSARIA BONSIGNORE (Unità di personale esterno)

Prodotto

• Istituto di biomedicina e di immunologia molecolare \"Alberto Monroy\" (IBIM) (Istituto)
• Immunopatologia e Farmacologia nelle Pneumopatie: studi dei meccanismi molecolari in vivo e in modelli in vitro (ME.P01.014.006) (Modulo)
• Immunopatologia e Farmacologia Clinica e Sperimentale nelle malattie respiratorie (ME.P01.014.005) (Modulo)
• Modelli ex vivo/in vitro per lo studio dell'immunopatologia e della farmacologia nelle pneumopatie (ME.P01.014.007) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• European respiratory review (Rivista)

Insieme di parole chiave di

• Keywords of "Advances in asthma pathophysiology: stepping forward from the Maurizio Vignola experience." (Insieme di parole chiave)