http://www.cnr.it/ontology/cnr/individuo/prodotto/ID323543

A Revertible, Autonomous, Self-Assembled DNA-Origami Nanoactuator (Articolo in rivista)

Type

Label

A Revertible, Autonomous, Self-Assembled DNA-Origami Nanoactuator (Articolo in rivista) (literal)

Anno

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

Alternative label

Marini, Monica; Piantanida, Luca; Musetti, Rita; Bek, Alpan; Dong, Mingdong; Besenbacher, Flemming; Lazzarino, Marco; Firrao, Giuseppe (2011)
A Revertible, Autonomous, Self-Assembled DNA-Origami Nanoactuator
in Nano letters (Print)
(literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

Marini, Monica; Piantanida, Luca; Musetti, Rita; Bek, Alpan; Dong, Mingdong; Besenbacher, Flemming; Lazzarino, Marco; Firrao, Giuseppe (literal)

Pagina inizio

Pagina fine

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Rivista

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Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

Note

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University of Udine; CBM Scrl; Aarhus University; Aarhus University; IOM CNR Lab TASC (literal)

Titolo

Abstract

A DNA-origami actuator capable of autonomous internal motion in accord to an external chemical signal was designed, built, operated and imaged. The functional DNA nanostructure consists of a disk connected to an external ring in two, diametrically opposite points. A single stranded DNA, named probe, was connected to two edges of the disk perpendicularly to the axis of constrain. In the presence of a hybridizing target molecule, the probe coiled into a double helix that stretched the inner disk forcing the edges to move toward each other. The addition of a third single stranded molecule that displaced the target from the probe restored the initial state of the origami. Operation, dimension and shape were carefully characterized by combining microscopy and fluorescence techniques. (literal)

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