http://www.cnr.it/ontology/cnr/individuo/prodotto/ID32031

Hybrid composite scaffolds prepared by sol-gel method for bone regeneration (Articolo in rivista)

Type

Label

Hybrid composite scaffolds prepared by sol-gel method for bone regeneration (Articolo in rivista) (literal)

Anno

Alternative label

Raucci MG; Guarino V; Ambrosio L; (2010)
Hybrid composite scaffolds prepared by sol-gel method for bone regeneration
in Composites science and technology
(literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

Pagina inizio

Pagina fine

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

Rivista

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#note

Note

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

Institute of Composite and Biomedical Materials, National Research Council (literal)

Titolo

Hybrid composite scaffolds prepared by sol-gel method for bone regeneration (literal)

Abstract

This study reports the synthesis and characterization of Hydroxyapatite (HA)/Polycaprolactone (PCL) hybrid composite materials synthesized by sol-gel method. The fabrication of scaffolds was performed by salt-leaching technique using NaCl as porogen agent. In the first step, the physico-chemical characterization of composite material was performed to evaluate the composition and the interaction between the organic/inorganic phases. In the second step, optimized scaffolds were bioactivated on the surface. The combined effect of scaffold morphology and surface bioactivity is ideal for bone tissue engineering, supporting bone cells adhesion, proliferation and differentiation. Here, a combined strategy involving biomimetic approach, using a supersaturated Simulated Body Fluid (SBF), and salt-leaching technique has been developed to grow hydroxyapatite in composite scaffolds able to regenerate the natural bone. (literal)

Prodotto di