Cancer phototherapy in living cells by multiphoton release of doxorubicin from gold nanospheres (Articolo in rivista)

Type
Label
  • Cancer phototherapy in living cells by multiphoton release of doxorubicin from gold nanospheres (Articolo in rivista) (literal)
Anno
  • 2013-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1039/c3tb20798f (literal)
Alternative label
  • Voliani, Valerio; Signore, Giovanni; Vittorio, Orazio; Faraci, Paolo; Luin, Stefano; Perez-Prieto, Julia; Beltram, Fabio (2013)
    Cancer phototherapy in living cells by multiphoton release of doxorubicin from gold nanospheres
    in Journal of Materials Chemistry B
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Voliani, Valerio; Signore, Giovanni; Vittorio, Orazio; Faraci, Paolo; Luin, Stefano; Perez-Prieto, Julia; Beltram, Fabio (literal)
Pagina inizio
  • 4225 (literal)
Pagina fine
  • 4230 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 1 (literal)
Rivista
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali
  • 6 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo
  • 34 (literal)
Note
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • University of Valencia; Consiglio Nazionale delle Ricerche (CNR); Scuola Normale Superiore di Pisa; Istituto Italiano di Tecnologia - IIT; University of New South Wales; University of New South Wales (literal)
Titolo
  • Cancer phototherapy in living cells by multiphoton release of doxorubicin from gold nanospheres (literal)
Abstract
  • Doxorubicin is a widely used but toxic cancer chemotherapeutic agent. In order to localize its therapeutic action and minimize side effects, it was covalently conjugated to peptide-encapsulated gold nanospheres by click-chemistry and then photo-released in a controlled fashion by a multiphoton process. Selective treatment of a chosen region in a 2D layer of U2Os cancer cells is shown by driving photorelease with 561 nm irradiation at mu W power. These results show promising directions for the development of practical applications based on nanocarriers that can ensure drug delivery with high spatial and temporal control. (literal)
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