http://www.cnr.it/ontology/cnr/individuo/prodotto/ID311845
Controlled Release of Tramadol from Mixed Matrix Membranes (Articolo in rivista)
- Type
- Label
- Controlled Release of Tramadol from Mixed Matrix Membranes (Articolo in rivista) (literal)
- Anno
- 2012-01-01T00:00:00+01:00 (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
- 10.6000/1929-6037.2012.01.02.8 (literal)
- Alternative label
L. Donato, G. Barbaro, E. Drioli, C. Algieri (2012)
Controlled Release of Tramadol from Mixed Matrix Membranes
in Journal of Membrane and Separation Technology
(literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- L. Donato, G. Barbaro, E. Drioli, C. Algieri (literal)
- Pagina inizio
- Pagina fine
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#url
- http://www.lifescienceglobal.com/home/cart?view=product&id=319 (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
- Rivista
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
- ITM - Istituto per la tecnologia delle membrane (literal)
- Titolo
- Controlled Release of Tramadol from Mixed Matrix Membranes (literal)
- Abstract
- In this work mixed matrix membranes (zeolite loaded) were prepared and tested as potential devices for the
controlled release of tramadol hydrochloride. Due to the hydrophilic nature of the drug, a hydrophobic polymer
(polydimethylsiloxane) was chosen for the membrane preparation. NaX zeolites was added to PDMS matrix as
modulating agent with the aim to obtain a linear and adequate delivery of the drug in the time as required by the
therapeutic needs of this opioid.
About the different investigated systems, the PDMS membrane containing 17 wt% of zeolite and 0.2 wt% of drug seems
to be the most promising for application as transdermal device. Different mathematical models (Zero order, First order,
Higuchi, Bhaskar, and Korsemeyer-Peppas) were used to interpret the drug release mechanism from the different Mixed
matrix membranes. The experimental data showed good fit with three different models: Higuchi, Bhaskar and
Korsemeyer-Peppas. (literal)
- Prodotto di
- Autore CNR
- Insieme di parole chiave
Incoming links:
- Prodotto
- Autore CNR di
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi
- Insieme di parole chiave di