Light-responsive hybrid sponges for on demand chemical release (Comunicazione a convegno)

Type

• Prodotto della ricerca (Classe)
• Comunicazione a convegno (Classe)

Label

• Light-responsive hybrid sponges for on demand chemical release (Comunicazione a convegno) (literal)

Anno

• 2014-01-01T00:00:00+01:00 (literal)

Alternative label

• Matteini P, Martina MR, Giambastiani G, Tatini F, Cascella R, Ratto F, Cecchi C, Caminati G, Dei L, Pini R (2014)
  Light-responsive hybrid sponges for on demand chemical release
  in E-MRS, Strasburgo (Francia), 27-31/05/2013
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Matteini P, Martina MR, Giambastiani G, Tatini F, Cascella R, Ratto F, Cecchi C, Caminati G, Dei L, Pini R (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Institute of Applied Physics \"Nello Carrara\", National Research Council, via Madonna del Piano 10, 50019, Sesto Fiorentino, Italy; Department of Chemistry and CSGI Consortium, University of Florence, via della Lastruccia 13, 50019, Florence, Italy; Institute of Chemistry of Organometallic Compounds, National Research Council, via Madonna del Piano 10, 50019, Sesto Fiorentino, Italy; Department of Biochemical Sciences, University of Florence, Viale G.B. Morgagni 50, 50134, Florence, Italy (literal)

Titolo

• Light-responsive hybrid sponges for on demand chemical release (literal)

Abstract

• Stimuli-responsive biomaterials have attracted much attention for their prospective application in several fields including biomedicine, biotechnology and biosensing. On the basis of our previous work [1], we have succeeded in fabricating an implantable device for on demand chemical release in the form of a light-activated nanocomposite sponge [2]. The sponge consists of a porous chitosan scaffold containing a dispersion of gold nanorods (GNRs), which acts as an absorber of an incoming laser light, and of thermosensitive PCL-PEG-PCL micelles, which serve as a reservoir for the drug molecules to be released. The photothermal response of the GNRs contained inside the sponge triggers a contraction in proximal micelles, thus promoting the expulsion of the drug that in turn is released to the external environment. The peculiar features of the nanocomposite sponges impart a number of interesting characteristics to this drug release system, including the possibility of spatially confining the therapeutic treatment as well as of a precise control over the amount of released drug as a function of duration and power of the excitation light. [1] Matteini P et al. ?Chitosan films doped with gold nanorods as laser-activatable hybrid bioadhesives?. Adv Mater 22 4313 (2010) [2] Matteini P et al. ?Light-responsive nanocomposite sponges for on demand chemical release with high spatial and dosage control? J Mater Chem B DOI: 10.1039/C2TB00310D (2013) (literal)

Prodotto di

• Institute of applied physics \"Nello Carrara\" (IFAC) (Istituto)
• Istituto di chimica dei composti organo metallici (ICCOM) (Istituto)

Autore CNR

• GIULIANO GIAMBASTIANI (Unità di personale interno)
• PAOLO MATTEINI (Unità di personale interno)
• FULVIO RATTO (Persona)
• ROBERTO PINI (Persona)

Incoming links:

Prodotto

• Istituto di chimica dei composti organo metallici (ICCOM) (Istituto)
• Institute of applied physics \"Nello Carrara\" (IFAC) (Istituto)

Autore CNR di

• GIULIANO GIAMBASTIANI (Unità di personale interno)
• ROBERTO PINI (Persona)
• PAOLO MATTEINI (Unità di personale interno)
• FULVIO RATTO (Persona)
• http://www.cnr.it/ontology/cnr/individuo/unitaDiPersonaleEsterno/ID23210