Terahertz probe of individual subwavelength objects in a water environment (Articolo in rivista)

Type
Label
  • Terahertz probe of individual subwavelength objects in a water environment (Articolo in rivista) (literal)
Anno
  • 2014-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1002/lpor.201300224 (literal)
Alternative label
  • Masini L.[ 1,2,3 ]; Meucci S.[ 1,2,3 ]; Xu J.[ 1,2 ]; Degl'Innocenti R.[ 1,2,4 ]; Castellano F.[ 1,2 ]; Beere H.E.[ 4 ]; Ritchie D.[ 4 ] ; Balduzzi D.[ 5 ] ; Puglisi R.[ 5 ]; Galli A.[ 5 ]; Beltram F.[ 1,2,3 ]; Vitiello M.S.[ 1,2 ]; Cecchini M.[ 1,2 ] ; Tredicucci A.[ 1,2] (2014)
    Terahertz probe of individual subwavelength objects in a water environment
    in Laser & photonics reviews (Internet)
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Masini L.[ 1,2,3 ]; Meucci S.[ 1,2,3 ]; Xu J.[ 1,2 ]; Degl'Innocenti R.[ 1,2,4 ]; Castellano F.[ 1,2 ]; Beere H.E.[ 4 ]; Ritchie D.[ 4 ] ; Balduzzi D.[ 5 ] ; Puglisi R.[ 5 ]; Galli A.[ 5 ]; Beltram F.[ 1,2,3 ]; Vitiello M.S.[ 1,2 ]; Cecchini M.[ 1,2 ] ; Tredicucci A.[ 1,2] (literal)
Pagina inizio
  • 734 (literal)
Pagina fine
  • 742 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#url
  • http://www.scopus.com/inward/record.url?eid=2-s2.0-84906827390&partnerID=q2rCbXpz (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 8 (literal)
Rivista
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo
  • 5 (literal)
Note
  • Scopu (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • [ 1 ] CNR, Ist Nanosci, NEST, I-56127 Pisa, Italy [ 2 ] Scuola Normale Super Pisa, I-56127 Pisa, Italy [ 3 ] Ist Italiano Tecnol, Ctr Nanotechnol Innovat NEST, I-56127 Pisa, Italy [ 4 ] Univ Cambridge, Cavendish Lab, Cambridge CB3 0HE, England [ 5 ] Ist Sperimentale Italiano Lazzaro Spallanzani, I-26027 Rivolta Dadda, Cremona, Italy (literal)
Titolo
  • Terahertz probe of individual subwavelength objects in a water environment (literal)
Abstract
  • Terahertz (THz) spectroscopy and imaging have been heralded for some time as potentially revolutionary techniques for biomedical applications. Label-free detection of molecules and recognition of molecular events are often mentioned as the most exciting possibilities. A crucial practical goal, however, is the ability to perform such measurements on tiny amounts of biological fluids or even on individual organic structures. Living cells, for instance, have diameters at most of some tens of micrometers, i.e. at least ?/10 even for few-THz radiation. Furthermore, all analyses relevant for a biological perspective must be performed in a water environment, which presents a strong absorption across the whole THz spectral range, severely limiting the penetration of the electromagnetic field. Here, it is shown how both issues can be overcome with a lab-on-a-chip approach based on a microfluidic platform coupled to a plasmonic antenna. Using a quantum cascade laser as THz illumination source, liquid volumes down to the picoliter range are probed, and direct operation on individual 10-?m diameter microparticles flowing in water is shown. The present demonstration opens the way to the development of THz biosensing of individual living cells and small probe volumes. A THz lab-on-a-chip device based on a microfluidic platform coupled to an integrated plasmonic antenna is shown. Using a quantum cascade laser as illumination source, liquid volumes down to the picoliter range are probed. A proof-of-concept experiment is performed in which single 10-?m diameter (~ ?/10) microparticles flowing in water are identified and investigated. The present demonstration opens the way to the development of THz biosensing of individual living cells and small probe volumes. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. (literal)
Prodotto di
Autore CNR
Insieme di parole chiave

Incoming links:


Autore CNR di
Prodotto
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi
Insieme di parole chiave di
data.CNR.it