Performance assessment of time-domain optical brain imagers, part 1: basic instrumental performance protocol (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Performance assessment of time-domain optical brain imagers, part 1: basic instrumental performance protocol (Articolo in rivista) (literal)

Anno

• 2014-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1117/1.JBO.19.8.086010 (literal)

Alternative label

• Wabnitz, Heidrun; Taubert, Dieter Richard; Mazurenka, Mikhail; Steinkellner, Oliver; Jelzow, Alexander; Macdonald, Rainer; Milej, Daniel; Sawosz, Piotr; Kacprzak, Michal; Liebert, Adam; Cooper, Robert; Hebden, Jeremy; Pifferi, Antonio; Farina, Andrea; Bargigia, Ilaria; Contini, Davide; Caffini, Matteo; Zucchelli, Lucia; Spinelli, Lorenzo; Cubeddu, Rinaldo; Torricelli, Alessandro (2014)
  Performance assessment of time-domain optical brain imagers, part 1: basic instrumental performance protocol
  in Journal of biomedical optics
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Wabnitz, Heidrun; Taubert, Dieter Richard; Mazurenka, Mikhail; Steinkellner, Oliver; Jelzow, Alexander; Macdonald, Rainer; Milej, Daniel; Sawosz, Piotr; Kacprzak, Michal; Liebert, Adam; Cooper, Robert; Hebden, Jeremy; Pifferi, Antonio; Farina, Andrea; Bargigia, Ilaria; Contini, Davide; Caffini, Matteo; Zucchelli, Lucia; Spinelli, Lorenzo; Cubeddu, Rinaldo; Torricelli, Alessandro (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 19 (literal)

Rivista

• Journal of biomedical optics (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali

• 12 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 8 (literal)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• PTB; Polish Academy of Science; University College London; Polytechnic University of Milan; Consiglio Nazionale delle Ricerche (CNR); Istituto Italiano di Tecnologia - IIT (literal)

Titolo

• Performance assessment of time-domain optical brain imagers, part 1: basic instrumental performance protocol (literal)

Abstract

• Performance assessment of instruments devised for clinical applications is of key importance for validation and quality assurance. Two new protocols were developed and applied to facilitate the design and optimization of instruments for time-domain optical brain imaging within the European project nEUROPt. Here, we present the \"Basic Instrumental Performance\" protocol for direct measurement of relevant characteristics. Two tests are discussed in detail. First, the responsivity of the detection system is a measure of the overall efficiency to detect light emerging from tissue. For the related test, dedicated solid slab phantoms were developed and quantitatively spectrally characterized to provide sources of known radiance with nearly Lambertian angular characteristics. The responsivity of four time-domain optical brain imagers was found to be of the order of 0.1 m(2) sr. The relevance of the responsivity measure is demonstrated by simulations of diffuse reflectance as a function of source-detector separation and optical properties. Second, the temporal instrument response function (IRF) is a critically important factor in determining the performance of time-domain systems. Measurements of the IRF for various instruments were combined with simulations to illustrate the impact of the width and shape of the IRF on contrast for a deep absorption change mimicking brain activation. (C) The Authors. Published by SPIE under a Creative Commons Attribution 3.0 Unported License. (literal)

Prodotto di

• Istituto di fotonica e nanotecnologie (IFN) (Istituto)

Autore CNR

• ANDREA FARINA (Persona)
• LORENZO CLEMENTE SPINELLI (Unità di personale interno)
• ANTONIO GIOVANNI PIFFERI (Persona)
• RINALDO CUBEDDU (Unità di personale esterno)

Insieme di parole chiave

• Parole chiave di "Performance assessment of time-domain optical brain imagers, part 1: basic instrumental performance protocol" (Insieme di parole chiave)

Incoming links:

Prodotto

• Istituto di fotonica e nanotecnologie (IFN) (Istituto)

Autore CNR di

• RINALDO CUBEDDU (Unità di personale esterno)
• LORENZO CLEMENTE SPINELLI (Unità di personale interno)
• ANTONIO GIOVANNI PIFFERI (Persona)
• ANDREA FARINA (Persona)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Journal of biomedical optics (Rivista)

Insieme di parole chiave di

• Parole chiave di "Performance assessment of time-domain optical brain imagers, part 1: basic instrumental performance protocol" (Insieme di parole chiave)