The evolution of histidine biosynthesis in archaea: Insights into the his genes structure and organization in luca (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• The evolution of histidine biosynthesis in archaea: Insights into the his genes structure and organization in luca (Articolo in rivista) (literal)

Anno

• 2009-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1007/s00239-009-9286-6 (literal)

Alternative label

• Fondi M.; Emiliani G.; Lio P.; Gribaldo S.; Fani R. (2009)
  The evolution of histidine biosynthesis in archaea: Insights into the his genes structure and organization in luca
  in Journal of molecular evolution
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Fondi M.; Emiliani G.; Lio P.; Gribaldo S.; Fani R. (literal)

Pagina inizio

• 512 (literal)

Pagina fine

• 526 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#url

• http://www.scopus.com/inward/record.url?eid=2-s2.0-72449198906&partnerID=q2rCbXpz (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 69 (literal)

Rivista

• Journal of molecular evolution (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 5 (literal)

Note

• ISI Web of Science (WOS) (literal)
• Scopu (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Department of Evolutionary Biology, University of Florence, Via Romana 17-19, Florence 50125; Tree and Timber Institute, National Research Council, Via Biasi, 75, San Michele all'Adige, Trento 38010; Computer Laboratory, University of Cambridge, 15 JJ Thomson Avenue, Cambridge CB3 0FD; Department of Microbiology, Institut Pasteur, BMGE Unit, Paris (literal)

Titolo

• The evolution of histidine biosynthesis in archaea: Insights into the his genes structure and organization in luca (literal)

Abstract

• The available sequences of genes encoding the enzymes associated with histidine biosynthesis suggest that this is an ancient metabolic pathway that was assembled prior to the diversification of Bacteria, Archaea, and Eucarya. Paralogous duplication, gene elongation, and fusion events of several different his genes have played a major role in shaping this biosynthetic route. We have analyzed the structure and organization of histidine biosynthetic genes from 55 complete archaeal genomes and combined it with phylogenetic inference in order to investigate the mechanisms responsible for the assembly of the his pathway and the origin of his operons. We show that a wide variety of different organizations of his genes exists in Archaea and that some his genes or entire his (sub-)operons have been likely transferred horizontally between Archaea and Bacteria. However, we show that, in most Archaea, his genes are monofunctional (except for hisD) and scattered throughout the genome, suggesting that his operons might have been assembled multiple times during evolution and that in some cases they are the result of recent evolutionary events. An evolutionary model for the structure and organization of his genes in LUCA is proposed. © 2009 Springer Science+Business Media, LLC. (literal)

Prodotto di

• Salvaguardia e valorizzazione delle specie arboree LAMBARDI (AG.P04.036.001) (Modulo)

Autore CNR

• GIOVANNI EMILIANI (Unità di personale esterno)

Insieme di parole chiave

• Keywords of "The evolution of histidine biosynthesis in archaea: Insights into the his genes structure and organization in luca" (Insieme di parole chiave)

Incoming links:

Autore CNR di

• GIOVANNI EMILIANI (Unità di personale esterno)

Prodotto

• Salvaguardia e valorizzazione delle specie arboree LAMBARDI (AG.P04.036.001) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Journal of molecular evolution (Rivista)

Insieme di parole chiave di

• Keywords of "The evolution of histidine biosynthesis in archaea: Insights into the his genes structure and organization in luca" (Insieme di parole chiave)