Filamentous Bacteriophage Fd as an Antigen Delivery System in Vaccination (Articolo in rivista)

Type
Label
  • Filamentous Bacteriophage Fd as an Antigen Delivery System in Vaccination (Articolo in rivista) (literal)
Anno
  • 2012-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.3390/ijms13045179 (literal)
Alternative label
  • Antonella Prisco1,* and Piergiuseppe De Berardinis2,* (2012)
    Filamentous Bacteriophage Fd as an Antigen Delivery System in Vaccination
    in International journal of molecular sciences (Print)
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Antonella Prisco1,* and Piergiuseppe De Berardinis2,* (literal)
Pagina inizio
  • 5179 (literal)
Pagina fine
  • 5194 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 13 (literal)
Rivista
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo
  • 4 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • 1Institute of Genetics and Biophysics, CNR, via P. Castellino 111, 80131, Naples, Italy (literal)
Titolo
  • Filamentous Bacteriophage Fd as an Antigen Delivery System in Vaccination (literal)
Abstract
  • Peptides displayed on the surface of filamentous bacteriophage fd are able to induce humoral as well as cell-mediated immune responses, which makes phage particles an attractive antigen delivery system to design new vaccines. The immune response induced by phage-displayed peptides can be enhanced by targeting phage particles to the professional antigen presenting cells, utilizing a single-chain antibody fragment that binds dendritic cell receptor DEC-205. Here, we review recent advances in the use of filamentous phage fd as a platform for peptide vaccines, with a special focus on the use of phage fd as an antigen delivery platform for peptide vaccines in Alzheimer's Disease and cancer. (literal)
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Autore CNR

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