http://www.cnr.it/ontology/cnr/individuo/prodotto/ID307849
Observer reproducibility of results from a low-dose I-123-metaiodobenzylguanidine cardiac imaging protocol in patients with heart failure (Articolo in rivista)
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- Observer reproducibility of results from a low-dose I-123-metaiodobenzylguanidine cardiac imaging protocol in patients with heart failure (Articolo in rivista) (literal)
- Anno
- 2013-01-01T00:00:00+01:00 (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
- 10.1007/s00259-013-2461-4 (literal)
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Pellegrino, Teresa; Petretta, Mario; De Luca, Serena; Paolillo, Stefania; Boemio, Antonio; Carotenuto, Raffaella; Petretta, Maria Piera; di Nuzzo, Carmine; Perrone-Filardi, Pasquale; Cuocolo, Alberto (2013)
Observer reproducibility of results from a low-dose I-123-metaiodobenzylguanidine cardiac imaging protocol in patients with heart failure
in European journal of nuclear medicine and molecular imaging (Print)
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- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- Pellegrino, Teresa; Petretta, Mario; De Luca, Serena; Paolillo, Stefania; Boemio, Antonio; Carotenuto, Raffaella; Petretta, Maria Piera; di Nuzzo, Carmine; Perrone-Filardi, Pasquale; Cuocolo, Alberto (literal)
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- Consiglio Nazionale delle Ricerche (CNR); University of Naples Federico II; SDN Fdn; University of Naples Federico II (literal)
- Titolo
- Observer reproducibility of results from a low-dose I-123-metaiodobenzylguanidine cardiac imaging protocol in patients with heart failure (literal)
- Abstract
- PURPOSE: Imaging of the cardiac autonomic system with (123)I-metaiodobenzylguanidine (MIBG) is useful in the evaluation of patients with a variety of cardiac conditions, including heart failure (HF), but few data are available about the reproducibility of this technique. We assessed the observer reproducibility of the results from a low-dose (123)I-MIBG cardiac imaging protocol in patients with HF. METHODS: A total of 74 patients (62 men, age 67 ± 10 years) with HF and left ventricular systolic dysfunction (ejection fraction 31 ± 7 %) underwent low-dose (111 MBq) planar and single-photon emission computed tomography (SPECT) (123)I-MIBG cardiac sympathetic imaging. The intraclass coefficient of correlation (ICC), Lin's concordance correlation coefficient, and Bland-Altman analysis were used to evaluate the intraobserver and interobserver reproducibility of early and late heart-to-mediastinum (H/M) ratios and of defect scores on SPECT images. The ? statistic was used to evaluate the concordance rates for the identification of patients with a low H/M ratio (<1.60) on late planar imaging. RESULTS: The differences between measurements obtained twice by the same examiner and by two examiners were negligible for both early and late H/M ratios and for SPECT defect scores. These findings were confirmed by the results of Bland-Altman analysis, and ICC and Lin's coefficient values were excellent (>0.90) for all measurements. For the identification of patients with a low H/M ratio, the ? values were 0.90 for intraobserver concordance and 0.83 for interobserver concordance. CONCLUSION: The present study showed a high observer reproducibility of planar H/M ratios and SPECT defect scores using a low-dose (123)I-MIBG cardiac imaging protocol in patients with HF. (literal)
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