Herbal Medicine and Natural Products Analysis: A Challenging Issue for Capillary Electromigration and Chromatographic Techniques (Comunicazione a convegno)

Type
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  • Herbal Medicine and Natural Products Analysis: A Challenging Issue for Capillary Electromigration and Chromatographic Techniques (Comunicazione a convegno) (literal)
Anno
  • 2014-01-01T00:00:00+01:00 (literal)
Alternative label
  • Fanali Salvatore (2014)
    Herbal Medicine and Natural Products Analysis: A Challenging Issue for Capillary Electromigration and Chromatographic Techniques
    in The 3rd Annual Meeting of GP-TCM RA and The 5th Annual Conference o the Specialist Committee of TCM Pharmaceutical Analysis of WFCMS, Nanjing, China, 18-20 July 2014
    (literal)
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  • Fanali Salvatore (literal)
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  • 6 (literal)
Rivista
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  • Istituto di Metodologie Chimiche (literal)
Titolo
  • Herbal Medicine and Natural Products Analysis: A Challenging Issue for Capillary Electromigration and Chromatographic Techniques (literal)
Abstract
  • Traditional Chinese medicine (TCM) has been used world wide for thousands of years since its development in China to treat a large number of health problems. Very often the prod ucts used contain several active components which are effective for specific illnesses. Due to the presence of several compounds there is a need to perform accurate analysis to determine the composition of TCM. Defining the composition is necessary for both health and safety problems, in order to understand the biological/pharmacological effects of certain compounds, their interactions with other drugs, discovering counterfeit products (very often introduced in the market especially through internet business) etc. So far, analytical methods used for the analysis of TCM or herbal products include several conventional separation and physical techniques. Gas chromatography/GC, liquid chro matography/LC, mass spectrometry/MS, nuclear magnetic resonance/NMR are those most applied in the field of TCM, offering excellent results which can be used by a large number of State Institution Control laboratories, industries, researchers, etc. In recent years miniaturization has been introduced in var ious fields of separation science offering several advantages over conventional methodologies, e.g., reducing (i) the sol vent and samples volumes, (ii) analysis time; achieving high efficiency, high resolution and high sensitivity; offering eco friendly methodologies and last but not least easier coupling with mass spectrometry. Among miniaturized techniques, capillary/nano-liquid chro matography (CLC/nano-LC) have been successfully proposed and applied in the separation and analysis of a large num ber of compounds in various field such as proteomics, drug, environmental, forensic, food, natural product analysis etc. The potentiality of these modern chromatographic techniques, may have utility for the analysis of TCM. The main advantages in using CLC/nano-LC is presented and discussed including the theoretical principles related to the tech nique. Some examples of practical separations of nutraceuticals, compounds present in natural products, drugs, enantiomers will also be considered. http://dx.doi.org/10.1016/j.eujim.2014.09.015 (literal)
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