Bioactive, Nanostructured Si-substituted Hydroxyapatite Coatings on Titanium Prepared by Pulsed Laser Deposition (Articolo in rivista)

Type
Label
  • Bioactive, Nanostructured Si-substituted Hydroxyapatite Coatings on Titanium Prepared by Pulsed Laser Deposition (Articolo in rivista) (literal)
Anno
  • 2015-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1002/jbm.b.33344 (literal)
Alternative label
  • J.V. Rau, I. Cacciotti, S. Laureti, M. Fosca, G. Varvaro, A. Latini (2015)
    Bioactive, Nanostructured Si-substituted Hydroxyapatite Coatings on Titanium Prepared by Pulsed Laser Deposition
    in Journal of biomedical materials research. Part B, Applied biomaterials
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • J.V. Rau, I. Cacciotti, S. Laureti, M. Fosca, G. Varvaro, A. Latini (literal)
Rivista
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • 1 Istituto di Struttura della Materia, Consiglio Nazionale delle Ricerche, Via del Fosso del Cavaliere, 100-00133 Rome, Italy 2 Universit?a di Roma \"Niccol?o Cusano\", Via Don Carlo Gnocchi, 3-00166 Rome, Italy 3 Dipartimento di Ingegneria dell'Impresa, Universit?a di Roma \"Tor Vergata\", UdR INSTM-\"Roma Tor Vergata\", Via del Politecnico, 1-00133 Rome, Italy 4 Istituto di Struttura della Materia, Consiglio Nazionale delle Ricerche, 00016 Monterotondo Scalo (RM), Italy 5 Dipartimento di Chimica, Universit?a di Roma \"La Sapienza\", Piazzale Aldo Moro, 5-00185 Rome, Italy (literal)
Titolo
  • Bioactive, Nanostructured Si-substituted Hydroxyapatite Coatings on Titanium Prepared by Pulsed Laser Deposition (literal)
Abstract
  • Aims: The aim of this work was to deposit siliconsubstituted hydroxyapatite (Si-HAp) coatings on titanium for biomedical applications, since it is known that Si-HAp is able to promote osteoblastic cells activity, resulting in the enhanced bone ingrowth. Materials and Methods: Pulsed laser deposition (PLD) method was used for coatings preparation. For depositions, Si-HAp targets (1.4 wt % of Si), made up from nanopowders synthesized by wet method, were used. Results: Microstructural and mechanical properties of the produced coatings, as a function of substrate temperature, were investigated by scanning electron and atomic force microscopies, X-ray diffraction, Fourier transform infrared spectroscopy, and Vickers microhardness. In the temperature range of 400-600?C, 1.4-1.5 mm thick Si-HAp films, presenting composition similar to that of the used target, were deposited. The prepared coatings were dense, crystalline, and nanostructured, characterized by nanotopography of surface and enhanced hardness. Whereas the substrate temperature of 750?C was too high and led to the HAp decomposition. Moreover, the bioactivity of coatings was evaluated by in vitro tests in an osteoblastic/osteoclastic culture medium (a- Modified Eagle's Medium). Conclusions: The prepared bioactive Si-HAp coatings could be considered for applications in orthopedics and dentistry to improve the osteointegration of bone implants. (literal)
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