An artificial life model for predicting the tertiary structure of unknown proteins that emulates the folding process (Articolo in rivista)

Type
Label
  • An artificial life model for predicting the tertiary structure of unknown proteins that emulates the folding process (Articolo in rivista) (literal)
Anno
  • 1995-01-01T00:00:00+01:00 (literal)
Alternative label
  • Calabretta, R; Nolfi, S; Parisi, D (1995)
    An artificial life model for predicting the tertiary structure of unknown proteins that emulates the folding process
    in Lecture notes in computer science; Springer, Berlin (Germania)
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Calabretta, R; Nolfi, S; Parisi, D (literal)
Pagina inizio
  • 862 (literal)
Pagina fine
  • 875 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 929 (literal)
Rivista
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali
  • 14 (literal)
Note
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • Consiglio Nazionale delle Ricerche (CNR) Consiglio Nazionale delle Ricerche (CNR) Consiglio Nazionale delle Ricerche (CNR) (literal)
Titolo
  • An artificial life model for predicting the tertiary structure of unknown proteins that emulates the folding process (literal)
Abstract
  • We present an ''ab initio'' method that tries to determine the tertiary structure of unknown proteins by modelling the folding process without using potentials extracted from known protein structures. We have been able to obtain appropriate matrices of folding potentials, i.e. 'forces' able to drive the folding process to produce correct tertiary structures, using a genetic algorithm. Some initial simulations that try to simulate the folding process of a fragment of the crambin that results in an alpha-helix, have yielded good results. We discuss some general implications of an Artificial Life approach to protein folding which makes an attempt at simulating the actual folding process rather than just trying to predict its final result. (literal)
Editore
Prodotto di
Autore CNR

Incoming links:


Autore CNR di
Prodotto
Editore di
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi
data.CNR.it